Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.45 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12394324 | 0.84 | KDM4E (0.66) | PPM1BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5191893 | 0.83 | PPM1B (0.60) | PPM1BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL148241 | 0.82 | ACMSD (0.65) | PPM1BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30611811 | 0.82 | ACMSD (0.65) | PPM1BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL21857213 | 0.81 | PPM1B (0.50) | PPM1BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29436316 | 0.80 | PPM1B (0.75) | PPM1BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL710309 | 0.80 | PPM1B (0.75) | PPM1BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL23499274 | 0.78 | PPM1B (0.79) | PPM1BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29908977 | 0.78 | PPM1B (0.79) | PPM1BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL21857594 | 0.77 | PPM1B (0.67) | PPM1BKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020080979-A1 | PFKFB3 INHIBITORS AND THEIR USES | GERO DISCOVERY LIMITED LIABILITY COMPANY (RU) | 2020-04-23 | — | — | WO | disclosed |