SCHEMBL29908977

SCHEMBL29908977

Nc1cc(-c2ccc(-c3ccc(C(=O)O)c(N)c3)cc2)ccc1C(=O)O

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 1/20 0.79
KDM4E B2RXH2 6/20 0.65
KMT2A Q03164 4/20 0.65
GFER P55789 1/20 0.65
RXFP1 Q9HBX9 1/20 0.65
ALDH1A1 P00352 5/20 0.55
HPGD P15428 2/20 0.55
HSD17B10 Q99714 2/20 0.55
ACMSD Q8TDX5 3/20 0.53
HNF4A P41235 2/20 0.53
TDP1 Q9NUW8 3/20 0.53
CYP3A4 P08684 2/20 0.53
ALOX15 P16050 2/20 0.53
IKBKB O14920 1/20 0.50
IDO1 P14902 1/20 0.50
MCL1 Q07820 4/20 0.48
DHFR P00374 1/20 0.48
DCLRE1A Q6PJP8 1/20 0.47
DCLRE1B Q9H816 1/20 0.47
MAPT P10636 5/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23499274 1.00 PPM1B (0.79) PPM1BKDM4EKMT2AGFERRXFP1
SCHEMBL710309 0.98 PPM1B (0.75) PPM1BKDM4EKMT2AGFERRXFP1
SCHEMBL29436316 0.98 PPM1B (0.75) PPM1BKDM4EKMT2AGFERRXFP1
SCHEMBL2575452 0.94 PPM1B (0.71) PPM1BKDM4EKMT2AGFERRXFP1
SCHEMBL30456877 0.94 PPM1B (0.71) PPM1BKDM4EKMT2AGFERRXFP1
SCHEMBL30314350 0.93 PPM1B (0.70) PPM1BKDM4EKMT2AGFERRXFP1
SCHEMBL17177763 0.93 PPM1B (0.70) PPM1BKDM4EKMT2AGFERRXFP1
SCHEMBL6851164 0.92 PPM1B (0.74) PPM1BKDM4EKMT2AGFERRXFP1
SCHEMBL30504245 0.92 PPM1B (0.69) PPM1BKDM4EKMT2AGFERRXFP1
SCHEMBL17938293 0.92 PPM1B (0.69) PPM1BKDM4EKMT2AGFERRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4301711-A1 HIGH OPTICAL TRANSMISSION AMPHIPHOBIC SURFACES; AND METHODS OF FORMING THEM UCL Business Ltd (GB) 2024-01-10 EP claimed
WO-2022184793-A1 HIGH OPTICAL TRANSMISSION AMPHIPHOBIC SURFACES; AND METHODS OF FORMING THEM UCL BUSINESS LTD (GB) 2022-09-09 WO claimed
US-20240424488-A1 High-Entropy Metal-Organic Frameworks NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC 2024-12-26 US disclosed
EP-4301711-A1 HIGH OPTICAL TRANSMISSION AMPHIPHOBIC SURFACES; AND METHODS OF FORMING THEM UCL Business Ltd (GB) 2024-01-10 EP disclosed
US-20230011770-A1 LANTHANIDE COMPOUNDS FOR LUMINESCENCE \"TURN-ON\" DETECTION UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2023-01-12 US disclosed
EP-4073066-A2 LANTHANIDE COMPOUNDS FOR LUMINESCENCE \"TURN-ON\" DETECTION University of Pittsburgh - of the Commonwealth System of Higher Education (US) 2022-10-19 EP disclosed
WO-2022184793-A1 HIGH OPTICAL TRANSMISSION AMPHIPHOBIC SURFACES; AND METHODS OF FORMING THEM UCL BUSINESS LTD (GB) 2022-09-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230011770-A1 LANTHANIDE COMPOUNDS FOR LUMINESCENCE \"TURN-ON\" DETECTION LGALS4, LGALS9, LGALS3 PPM1B 3717/4885KDM4E 1125/4885KMT2A 2799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.