Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | SCN1A | P35498 | 3/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31299788 | 0.84 | L3MBTL1 (0.64) | CYP3A4CYP1A2CYP2C19L3MBTL1CA12 | |
| SCHEMBL7514004 | 0.82 | L3MBTL1 (0.58) | CYP3A4CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL27278463 | 0.82 | L3MBTL1 (0.62) | L3MBTL1METAP2CA1CA2CA12 | |
| SCHEMBL28181850 | 0.81 | L3MBTL1 (0.49) | CYP3A4ALDH1A1KDM4EL3MBTL1CA1 | |
| SCHEMBL9153315 | 0.80 | RAPGEF4 (0.54) | ALDH1A1KDM4EHSD17B10L3MBTL1KAT2B | |
| SCHEMBL9158249 | 0.80 | RAPGEF4 (0.54) | ALDH1A1KDM4EHSD17B10L3MBTL1KAT2B | |
| SCHEMBL11139997 | 0.80 | KDM4E (0.47) | CYP2C19ALDH1A1KDM4EHSD17B10L3MBTL1 | |
| SCHEMBL21857967 | 0.79 | TTR (0.54) | CYP3A4CYP1A2CYP2C9CYP2C19SCN1A | |
| SCHEMBL9152694 | 0.78 | RAPGEF4 (0.55) | ALDH1A1KDM4EHSD17B10L3MBTL1KAT2B | |
| SCHEMBL7520863 | 0.78 | L3MBTL1 (0.50) | HSD17B10L3MBTL1CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5241057-A | Blue shades | BAYER AKTIENGESELLSHAFT (DE) | 1993-08-31 | — | — | US | disclosed |
| US-4968783-A | FIBER-REACTIVE DYES FOR COTTON | CIBA-GEIGY CORPORATION (US) | 1990-11-06 | — | — | US | disclosed |
| EP-0084314-B1 | REACTIVE DISAZO DYES | BAYER AG (DE) | 1986-07-30 | — | — | EP | disclosed |
| EP-0083052-B1 | REACTIVE DISAZO DYES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING AND PRINTING HYDROXYL OR NITROGEN CONTAINING FIBROUS MATERIALS | BAYER AG (DE) | 1985-11-13 | — | — | EP | disclosed |
| EP-0084314-A2 | Reactive disazo dyes | BAYER AG (DE) | 1983-07-27 | — | — | EP | disclosed |
| EP-0012716-B1 | MONOCHLOROTRIAZINE DYESTUFFS OF THE PYRAZOLONE SERIES, THEIR PREPARATION AND THEIR USE FOR DYEING AND PRINTING TEXTILE MATERIALS | CIBA-GEIGY AG (CH) | 1983-06-15 | — | — | EP | disclosed |
| US-4348318-A | DYEING AND PRINTING TEXTILES; MONOAZO, TRIAZINE, HYDRAZONE, AND PYRAZOLONE DYES | CIBA-GEIGY CORPORATION (US) | 1982-09-07 | — | — | US | disclosed |
| EP-0012716-A1 | Monochlorotriazine dyestuffs of the pyrazolone series, their preparation and their use for dyeing and printing textile materials | CIBA-GEIGY AG (CH) | 1980-06-25 | — | — | EP | disclosed |
| US-4118232-A | Photographic material containing sulphonic acid group containing disazo dyestuffs | CIBA-GEIGY AG (CH) | 1978-10-03 | — | — | US | disclosed |
| US-4051123-A | Sulfonic-acid-group containing disazo dyestuffs | CIBA-GEIGY AG (CH) | 1977-09-27 | — | — | US | disclosed |
| US-3966705-A | Disulfo naphthalene containing fiber-reactive tetrazo dyes | CIBA-GEIGY CORPORATION (US) | 1976-06-29 | — | — | US | disclosed |