Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | CD40 | P25942 | 3/20 | 0.42 |
| ▸ | CD40LG | P29965 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10478980 | 0.87 | TTR (0.49) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL29358898 | 0.83 | CA12 (0.44) | TTRCD40CD40LGCA12CA9 | |
| SCHEMBL29355645 | 0.83 | CA12 (0.44) | TTRCD40CD40LGCA12CA9 | |
| SCHEMBL25745 | 0.83 | CA12 (0.44) | TTRCD40CD40LGCA12CA9 | |
| SCHEMBL10882233 | 0.82 | TTR (0.49) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL9627398 | 0.79 | CASP6 (0.58) | CA12CA9CA4CA7CA14 | |
| Sulfuric Acid SCHEMBL6255051 | 0.79 | CA12 (0.62) | CA12CA9CA4CA7CA14 | |
| SCHEMBL21857967 | 0.79 | TTR (0.54) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL8514648 | 0.78 | TTR (0.56) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL30950399 | 0.78 | TTR (0.56) | TTRFABP4CCNA2CDK2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000077520-A1 | LABELLING OF PEPTIDES AND PROTEINS | PROTEOSYS AG (DE) | 2000-12-21 | — | — | WO | claimed |
| EP-1059531-A1 | Labelling of peptides and proteins | Nordheim, Alfred, Prof. Dr. (DE) | 2000-12-13 | — | — | EP | claimed |
| EP-2719394-B1 | Peptides for treating amyloid-associated diseases | UNIV TEL AVIV FUTURE TECH DEV (IL) | 2015-07-29 | — | — | EP | disclosed |
| US-8993510-B2 | Peptides and methods using same for diagnosis and treatment of amyloid-associated disease | TEL AVIV UNIVERSITY FUTURE TECHNOLOGY DEVELOPMENT L.P. (IL) | 2015-03-31 | — | — | US | disclosed |
| EP-2719394-A1 | Peptides antibodies directed thereagainst for diagnosing and treating amyloid-associated diseases | Tel Aviv University Future Technology Development L.P. (IL) | 2014-04-16 | — | — | EP | disclosed |
| US-8697634-B2 | Peptides and methods using same for diagnosis and treatment of amyloid-associated disease | TEL AVIV UNIVERSITY FUTURE TECHNOLOGY DEVELOPMENT L.P. (IL) | 2014-04-15 | — | — | US | disclosed |
| US-20130338076-A1 | PEPTIDES AND METHODS USING SAME FOR DIAGNOSIS AND TREATMENT OF AMYLOID-ASSOCIATED DISEASE | TEL AVIV UNIVERSITY FUTURE TECHNOLOGY DEVELOPMENT L.P. (IL) | 2013-12-19 | — | — | US | disclosed |
| US-7781396-B2 | Peptides directed for diagnosis and treatment of amyloid-associated disease | TEL AVIV UNIVERSITY FUTURE TECHNOLOGY DEVELOPMENT L.P. (IL) | 2010-08-24 | — | — | US | disclosed |
| US-20100105608-A1 | Peptides and methods using same for diagnosis and treatment of amyloid-associated disease | TEL AVIV UNIVERSITY FUTURE TECHNOLOGY DEVELOPMENT L.P. (IL) | 2010-04-29 | — | — | US | disclosed |
| US-20100022459-A1 | Peptides directed for diagnosis and treatment of amyloid-associated diseases | Tel Aviv University Future Technology Development L.P (IL) | 2010-01-28 | — | — | US | disclosed |
| US-20070021345-A1 | Peptides antibodies directed thereagainst and methods using same for diagnosing and treating amyloid-associated diseases | TEL AVIV UNIVERSITY FUTURE TECHNOLOGY DEVELOPMENT L.P. (IL) | 2007-01-25 | — | — | US | disclosed |
| US-20060234947-A1 | Peptides antibodies directed thereagainst and methods using same for diagnosing and treating amyloid-associated diseases | Tel Aviv University Future Technology Development L.P (IL) | 2006-10-19 | — | — | US | disclosed |
| EP-1534310-A4 | PEPTIDES ANTIBODIES DIRECTED THEREAGAINST AND METHODS USING SAME FOR DIAGNOSING AND TREATING AMYLOID-ASSOCIATED DISEASES | UNIV TEL AVIV FUTURE TECH DEV (IL) | 2006-05-31 | — | — | EP | disclosed |
| EP-1638517-A2 | PEPTIDES ANTIBODIES DIRECTED THEREAGAINST AND METHODS USING SAME FOR DIAGNOSING AND TREATING AMYLOID-ASSOCIATED DISEASES | Tel Aviv University Future Technology Development L.P. (IL) | 2006-03-29 | — | — | EP | disclosed |
| EP-1534310-A2 | PEPTIDES ANTIBODIES DIRECTED THEREAGAINST AND METHODS USING SAME FOR DIAGNOSING AND TREATING AMYLOID-ASSOCIATED DISEASES | Tel Aviv University Future Technology Development L.P. (IL) | 2005-06-01 | — | — | EP | disclosed |
| US-20050020809-A1 | Peptides antibodies directed thereagainst and methods using same for diagnosing and treating amyloid-associated diseases | TEL AVIV UNIVERSITY FUTURE TECHNOLOGY DEVELOPMENT L.P. (IL) | 2005-01-27 | — | — | US | disclosed |
| WO-2005000193-A2 | PEPTIDES ANTIBODIES DIRECTED THEREAGAINST AND METHODS USING SAME FOR DIAGNOSING AND TREATING AMYLOID-ASSOCIATED DISEASES | TEL AVIV UNIVERSITY FUTURE TECHNOLOGY DEVELOPMENT L.P. (IL) | 2005-01-06 | — | — | WO | disclosed |
| WO-2003063760-A2 | PEPTIDES ANTIBODIES DIRECTED THEREAGAINST AND METHODS USING SAME FOR DIAGNOSING AND TREATING AMYLOID-ASSOCIATED DISEASES | TEL AVIV UNIVERSITY FUTURE TECHNOLOGY DEVELOPMENT L.P. (IL) | 2003-08-07 | — | — | WO | disclosed |
| US-4797480-A | New biologically active fluorescent cyclic nucleotides | UNIVERSITA DEGLI STUDI DI PARMA (IT) | 1989-01-10 | — | — | US | disclosed |
| EP-0205005-A2 | New biologically active fluorescent cyclic nucleotides | UNIVERSITA' DEGLI STUDI DI PARMA (IT) | 1986-12-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060234947-A1 | Peptides antibodies directed thereagainst and methods using same for diagnosing and treating amyloid-associated diseases | IAPP, NGLY1, APP | TTR 36/4885FABP4 3054/4885CCNA2 4802/4885 |
| US-20100022459-A1 | Peptides directed for diagnosis and treatment of amyloid-associated diseases | APP, IAPP, PEPD | TTR 5/4885FABP4 2745/4885CCNA2 4733/4885 |
| US-20130338076-A1 | PEPTIDES AND METHODS USING SAME FOR DIAGNOSIS AND TREATMENT OF AMYLOID-ASSOCIATED DISEASE | APP, IAPP, ENPEP | TTR 11/4885FABP4 2987/4885CCNA2 4722/4885 |
| US-20070021345-A1 | Peptides antibodies directed thereagainst and methods using same for diagnosing and treating amyloid-associated diseases | IAPP, NGLY1, APP | TTR 36/4885FABP4 3054/4885CCNA2 4802/4885 |
| US-20100105608-A1 | Peptides and methods using same for diagnosis and treatment of amyloid-associated disease | APP, IAPP, ENPEP | TTR 11/4885FABP4 2987/4885CCNA2 4722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.