Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC14B | O60729 | 2/20 | 0.36 |
| ▸ | CDC14A | Q9UNH5 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21858922 | 0.82 | ALDH1A1 (0.33) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL21858078 | 0.77 | CDC14B (0.41) | CDC14BCDC14AMAOAALDH1A1GLA | |
| SCHEMBL21858053 | 0.76 | CHAT (0.49) | MAOAALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL29054008 | 0.71 | CDC14B (0.40) | CDC14BCDC14AMAOAALDH1A1GLA | |
| SCHEMBL21858114 | 0.71 | HPRT1 (0.44) | ALDH1A1MAPTHPGDCYP3A4HSD17B10 | |
| SCHEMBL17223626 | 0.70 | NPC1 (0.49) | CDC14BCDC14AALDH1A1KDM4EMAPT | |
| SCHEMBL25056552 | 0.70 | CDC14B (0.47) | CDC14BCDC14AMAOAALDH1A1GLA | |
| SCHEMBL4126697 | 0.70 | MAOA (0.48) | CDC14BCDC14AMAOAALDH1A1GLA | |
| SCHEMBL19537979 | 0.70 | CA1 (0.44) | CDC14BCDC14AMAOAALDH1A1GLA | |
| SCHEMBL21858074 | 0.70 | CDC14B (0.44) | CDC14BCDC14AMAOAALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112955422-B | polycyclic compound | 三菱瓦斯化学株式会社 | 2023-08-22 | — | — | CN | disclosed |
| US-20210355058-A1 | POLYCYCLIC COMPOUNDS | MITSUBISHI GAS CHEMICAL CO (JP) | 2021-11-18 | — | — | US | disclosed |
| US-20210340317-A1 | POLYCYCLIC COMPOUNDS | REUTER CHEMISCHE APPARATEBAU E.K. (DE) | 2021-11-04 | — | — | US | disclosed |
| CN-112955422-A | Polycyclic compounds | 三菱瓦斯化学株式会社 | 2021-06-11 | — | — | CN | disclosed |
| WO-2020079225-A1 | POLYCYCLIC COMPOUNDS | REUTER CHEMISCHE APPARATEBAU E.K. (DE) | 2020-04-23 | — | — | WO | disclosed |
| WO-2020080558-A1 | POLYCYCLIC COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2020-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210340317-A1 | POLYCYCLIC COMPOUNDS | CBR1, C1R, CBR3 | CDC14B 4616/4885CDC14A 4547/4885MAOA 2050/4885 |
| US-20210355058-A1 | POLYCYCLIC COMPOUNDS | CBR1, CBR3, C1R | CDC14B 4529/4885CDC14A 4429/4885MAOA 2293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.