Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25009776 | 0.86 | — | — | |
| SCHEMBL25496890 | 0.72 | HRH4 (0.34) | HRH4HRH3 | |
| SCHEMBL2600181 | 0.72 | HRH4 (0.34) | HRH4HRH3 | |
| SCHEMBL14773334 | 0.71 | TSHR (0.42) | HRH4HRH3 | |
| SCHEMBL7834390 | 0.71 | HRH4 (0.43) | HRH4HRH3 | |
| SCHEMBL5839106 | 0.71 | HRH4 (0.39) | HRH4HRH3 | |
| SCHEMBL8960724 | 0.70 | — | — | |
| SCHEMBL546952 | 0.70 | — | — | |
| SCHEMBL21342880 | 0.70 | TSHR (0.42) | HRH4HRH3 | |
| SCHEMBL25080905 | 0.69 | HRH4 (0.32) | HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10618902-B2 | Substituted pyrido[2,3-d]pyrimidines as inhibitors of protein kinases | CELGENE CAR LLC (BM) | 2020-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10618902-B2 | Substituted pyrido[2,3-d]pyrimidines as inhibitors of protein kinases | PDXK, DCK, DTYMK | HRH4 2610/4885HRH3 2072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.