SCHEMBL2186085

SCHEMBL2186085

CCCCCCCCCCCCS(=O)(=O)O[Si](C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.46
CA2 P00918 14/20 0.42
PRKCA P17252 1/20 0.39
CA1 P00915 8/20 0.38
CA9 Q16790 7/20 0.38
CA12 O43570 3/20 0.38
CA7 P43166 3/20 0.38
CA14 Q9ULX7 3/20 0.38
CA3 P07451 2/20 0.38
CA4 P22748 2/20 0.38
CA6 P23280 2/20 0.38
CA5A P35218 2/20 0.38
CA5B Q9Y2D0 2/20 0.38
GLA P06280 1/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
EPHX2 P34913 1/20 0.36
RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10828829 1.00 FAAH (0.46) FAAHCA2PRKCACA1CA9
SCHEMBL1808306 0.81
SCHEMBL11039244 0.79
SCHEMBL31348986 0.79 MMP2 (0.30)
SCHEMBL10562270 0.77 FAAH (0.50) FAAHCA2PRKCACA1CA9
SCHEMBL14779380 0.77 ALDH1A1 (0.38) FAAHCA2PRKCACA1CA9
SCHEMBL10586169 0.77 FAAH (0.54) FAAHCA2CA1CA9CA12
SCHEMBL2383854 0.77 FAAH (0.54) FAAHCA2CA1CA9CA12
SCHEMBL22122808 0.77 FAAH (0.54) FAAHCA2CA1CA9CA12
SCHEMBL4957282 0.77 FAAH (0.54) FAAHCA2CA1CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2031031-B1 Use of a latent acid for improving adhesion SIKA TECHNOLOGY AG (CH) 2011-07-13 EP claimed
US-20090061239-A1 Use of a latent acid for adhesion promotion SIKA TECHNOLOGY AG (CH) 2009-03-05 US disclosed