Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 16/20 | 0.54 |
| ▸ | XIAP | P98170 | 2/20 | 0.53 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.53 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17609549 | 0.88 | TRPA1 (0.52) | TRPA1TRPV3 | |
| SCHEMBL17609589 | 0.75 | TRPV3 (0.53) | TRPA1XIAPBIRC2TRPV3 | |
| SCHEMBL17609761 | 0.73 | TRPA1 (0.69) | TRPA1 | |
| SCHEMBL19399983 | 0.73 | TRPA1 (0.69) | TRPA1 | |
| SCHEMBL17609759 | 0.73 | TRPA1 (0.69) | TRPA1 | |
| SCHEMBL19208099 | 0.72 | XIAP (0.69) | XIAPBIRC2 | |
| SCHEMBL29781821 | 0.72 | XIAP (0.69) | XIAPBIRC2 | |
| SCHEMBL19208097 | 0.72 | XIAP (0.69) | XIAPBIRC2 | |
| SCHEMBL21861301 | 0.72 | TRPA1 (0.60) | TRPA1 | |
| SCHEMBL21377327 | 0.69 | TRPA1 (0.50) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193880-B1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | LILLY CO ELI (US) | 2020-03-25 | — | — | EP | disclosed |