Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 5/20 | 0.50 |
| ▸ | PTGES | O14684 | 4/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 8/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21377114 | 0.88 | PTGES (0.52) | TRPA1PTGESCARM1 | |
| SCHEMBL21377105 | 0.81 | TRPA1 (0.48) | TRPA1PTGESCARM1PRMT6HDAC1 | |
| SCHEMBL16894106 | 0.80 | TRPA1 (0.50) | TRPA1PTGESKDM1AHDAC1 | |
| SCHEMBL16648021 | 0.76 | USP2 (0.50) | TRPA1KDM1AHDAC1 | |
| SCHEMBL18224072 | 0.74 | TRPA1 (0.53) | TRPA1PTGES | |
| SCHEMBL16894095 | 0.74 | TRPA1 (0.64) | TRPA1 | |
| SCHEMBL19917703 | 0.74 | TRPA1 (0.51) | TRPA1PTGES | |
| SCHEMBL16634937 | 0.74 | LOXL2 (0.55) | TRPA1 | |
| SCHEMBL19917702 | 0.74 | TRPA1 (0.53) | TRPA1PTGES | |
| SCHEMBL16648046 | 0.73 | TRPA1 (0.59) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3101015-B1 | HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE COMPRISING SAME | EA PHARMA CO LTD (JP) | 2019-09-18 | — | — | EP | disclosed |