Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL100858 | 0.85 | — | — | |
| SCHEMBL99563 | 0.78 | DGAT1 (0.32) | — | |
| SCHEMBL14973975 | 0.77 | POLB (0.33) | ALDH1A1 | |
| SCHEMBL14973973 | 0.77 | — | — | |
| SCHEMBL100600 | 0.71 | — | — | |
| SCHEMBL99873 | 0.69 | — | — | |
| SCHEMBL99676 | 0.68 | ALDH1A1 (0.37) | ALDH1A1LMNA | |
| SCHEMBL99395 | 0.68 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL21975051 | 0.66 | PRKCI (0.49) | — | |
| SCHEMBL100857 | 0.62 | DGAT1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343298-A1 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | Incyte Corporation (US) | 2011-07-13 | — | — | EP | disclosed |