Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21861536 | 0.86 | TRPA1 (0.44) | TRPA1RXFP1 | |
| SCHEMBL10280149 | 0.67 | TRPA1 (0.36) | TRPA1RXFP1 | |
| SCHEMBL15384375 | 0.66 | TRPA1 (0.37) | TRPA1RXFP1 | |
| SCHEMBL18175174 | 0.65 | ADORA2A (0.42) | — | |
| SCHEMBL7988189 | 0.64 | ADORA2A (0.42) | — | |
| SCHEMBL21861448 | 0.63 | TRPA1 (0.45) | TRPA1 | |
| SCHEMBL20161661 | 0.62 | TRPA1 (0.35) | TRPA1RXFP1 | |
| SCHEMBL7985623 | 0.62 | ADORA2A (0.45) | — | |
| SCHEMBL21861597 | 0.61 | TRPA1 (0.59) | TRPA1RXFP1 | |
| SCHEMBL21861543 | 0.61 | ADORA2A (0.38) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193880-B1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | LILLY CO ELI (US) | 2020-03-25 | — | — | EP | disclosed |