Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 9/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21861536 | 0.77 | TRPA1 (0.44) | TRPA1 | |
| SCHEMBL21861443 | 0.69 | — | — | |
| SCHEMBL21861602 | 0.63 | TRPA1 (0.41) | TRPA1 | |
| SCHEMBL19396074 | 0.62 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL14006396 | 0.61 | ALDH1A1 (0.43) | TRPA1 | |
| SCHEMBL841349 | 0.61 | CYP1A2 (0.42) | — | |
| SCHEMBL10031592 | 0.60 | KDM4E (0.66) | — | |
| SCHEMBL7988189 | 0.58 | ADORA2A (0.42) | — | |
| SCHEMBL26200822 | 0.58 | ALDH1A1 (0.36) | — | |
| SCHEMBL7985576 | 0.58 | CCNE1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193880-B1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | LILLY CO ELI (US) | 2020-03-25 | — | — | EP | disclosed |