Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 3/20 | 0.53 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.53 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NCS1 | P62166 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27756394 | 0.80 | CSNK1E (0.56) | CSNK1ECSNK1DCSNK1G3ABL1RAB9A | |
| SCHEMBL2188622 | 0.78 | CSNK1E (0.53) | CSNK1ECSNK1DCSNK1G3RAB9AALDH1A1 | |
| SCHEMBL2187098 | 0.76 | CSNK1E (0.51) | CSNK1ECSNK1DCSNK1G3KDM4ENPSR1 | |
| SCHEMBL2188423 | 0.75 | CSNK1E (0.56) | CSNK1ECSNK1DCSNK1G3RXFP1MEN1 | |
| SCHEMBL2187471 | 0.74 | CSNK1E (0.57) | CSNK1ECSNK1DCSNK1G3RAB9AKDM4E | |
| SCHEMBL4083190 | 0.74 | MAPK14 (0.53) | RAB9AKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL15541991 | 0.73 | CSNK1E (0.60) | CSNK1ECSNK1DCSNK1G3RXFP1RAB9A | |
| SCHEMBL27698601 | 0.73 | CSNK1E (0.49) | CSNK1ECSNK1DCSNK1G3RAB9ANPC1 | |
| SCHEMBL420828 | 0.72 | CSNK1E (0.59) | CSNK1ECSNK1DCSNK1G3RXFP1RAB9A | |
| SCHEMBL2187121 | 0.72 | CSNK1E (0.48) | CSNK1ECSNK1DCSNK1G3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343293-A1 | NOVEL PIPERIDIN-4-YL-THIAZOLE-CARBOXAMIDE ANALOGUES AS INHIBITORS OF T-CELL PROLIFERATION AND USES THEREOF | 4SC AG (DE) | 2011-07-13 | — | — | EP | disclosed |