Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 3/20 | 0.53 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.50 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.39 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2187098 | 0.89 | CSNK1E (0.51) | CSNK1ECSNK1DCSNK1G3SMN1; SMN2HSD17B10 | |
| SCHEMBL2188423 | 0.87 | CSNK1E (0.56) | CSNK1ECSNK1DCSNK1G3HTTSMN1; SMN2 | |
| SCHEMBL2187121 | 0.82 | CSNK1E (0.48) | CSNK1ECSNK1DCSNK1G3HTTALDH1A1 | |
| SCHEMBL2187360 | 0.80 | CSNK1E (0.49) | CSNK1ECSNK1DCSNK1G3SMN1; SMN2NPC1 | |
| SCHEMBL2188562 | 0.79 | LMNA (0.67) | HTTSMN1; SMN2ALOX15HSD17B10NPC1 | |
| SCHEMBL2186169 | 0.78 | CSNK1E (0.53) | CSNK1ECSNK1DCSNK1G3HTTSMN1; SMN2 | |
| SCHEMBL2187871 | 0.76 | LMNA (0.54) | CSNK1ECSNK1DHTTSMN1; SMN2ALOX15 | |
| SCHEMBL15541991 | 0.75 | CSNK1E (0.60) | CSNK1ECSNK1DCSNK1G3HTTSMN1; SMN2 | |
| SCHEMBL420828 | 0.74 | CSNK1E (0.59) | CSNK1ECSNK1DCSNK1G3HTTSMN1; SMN2 | |
| SCHEMBL2186848 | 0.73 | TSHR (0.52) | HTTSMN1; SMN2ALOX15NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343293-A1 | NOVEL PIPERIDIN-4-YL-THIAZOLE-CARBOXAMIDE ANALOGUES AS INHIBITORS OF T-CELL PROLIFERATION AND USES THEREOF | 4SC AG (DE) | 2011-07-13 | — | — | EP | disclosed |