Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 3/20 | 0.48 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TACR3 | P29371 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | EED | O75530 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2187098 | 0.86 | CSNK1E (0.51) | CSNK1ECSNK1DMAPTLMNAPOLB | |
| SCHEMBL2188622 | 0.82 | CSNK1E (0.53) | CSNK1ECSNK1DMAPTALDH1A1L3MBTL1 | |
| SCHEMBL2188423 | 0.82 | CSNK1E (0.56) | CSNK1ECSNK1DMAPTALDH1A1LMNA | |
| SCHEMBL2187360 | 0.82 | CSNK1E (0.49) | CSNK1ECSNK1DMAPTALDH1A1LMNA | |
| SCHEMBL2188562 | 0.81 | LMNA (0.67) | MAPTLMNAKMT2APOLBL3MBTL1 | |
| SCHEMBL15541991 | 0.77 | CSNK1E (0.60) | CSNK1ECSNK1DALDH1A1LMNAKMT2A | |
| SCHEMBL420828 | 0.76 | CSNK1E (0.59) | CSNK1ECSNK1DALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL27698601 | 0.75 | CSNK1E (0.49) | CSNK1ECSNK1DCSNK1G3KCNK3KCNK9 | |
| SCHEMBL15541229 | 0.74 | SMN1; SMN2 (0.64) | CSNK1ECSNK1DMAPTALDH1A1LMNA | |
| SCHEMBL2187871 | 0.72 | LMNA (0.54) | CSNK1ECSNK1DMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343293-A1 | NOVEL PIPERIDIN-4-YL-THIAZOLE-CARBOXAMIDE ANALOGUES AS INHIBITORS OF T-CELL PROLIFERATION AND USES THEREOF | 4SC AG (DE) | 2011-07-13 | — | — | EP | disclosed |