Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | POLQ | O75417 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12362493 | 0.88 | HSD17B1 (0.47) | HSD17B1HSD17B2AOC3ALDH1A1POLQ | |
| SCHEMBL12362494 | 0.80 | TP53 (0.57) | HSD17B1HSD17B2AOC3ALDH1A1KMT2A | |
| SCHEMBL1760632 | 0.74 | KMT2A (0.58) | ALDH1A1POLQKMT2A | |
| SCHEMBL23570956 | 0.73 | HSD17B2 (0.40) | HSD17B1HSD17B2AOC3 | |
| SCHEMBL5175586 | 0.72 | POLQ (0.49) | ALDH1A1POLQKMT2A | |
| SCHEMBL222344 | 0.72 | FASN (0.47) | ALDH1A1POLQKMT2A | |
| SCHEMBL4979577 | 0.72 | HSD17B1 (0.49) | HSD17B1HSD17B2HDAC8 | |
| SCHEMBL28392160 | 0.72 | HSD17B2 (0.47) | HSD17B1HSD17B2AOC3KMT2A | |
| SCHEMBL9456006 | 0.71 | FFAR1 (0.46) | HSD17B1HSD17B2AOC3ALDH1A1 | |
| SCHEMBL307215 | 0.71 | KMT2A (0.54) | ALDH1A1POLQKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3081213-B1 | TRICYCLIC COMPOUND | KYOWA KIRIN CO LTD (JP) | 2020-04-01 | — | — | EP | disclosed |