Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 6/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28801006 | 0.75 | ALDH1A1 (0.47) | KMT2A | |
| SCHEMBL9456051 | 0.74 | HSD17B2 (0.46) | HSD17B2HSD17B1 | |
| SCHEMBL12362493 | 0.74 | HSD17B1 (0.47) | HSD17B2HSD17B1KMT2AAOC3 | |
| SCHEMBL9456129 | 0.72 | HSD17B2 (0.46) | HSD17B2HSD17B1 | |
| SCHEMBL28391165 | 0.72 | ALDH1A1 (0.50) | KMT2A | |
| SCHEMBL21861794 | 0.72 | HSD17B1 (0.45) | HSD17B2HSD17B1KMT2AAOC3 | |
| SCHEMBL28392555 | 0.72 | HSD17B2 (0.55) | HSD17B2HSD17B1 | |
| SCHEMBL30504285 | 0.71 | BRD4 (0.62) | HSD17B2HSD17B1KMT2A | |
| SCHEMBL4979577 | 0.71 | HSD17B1 (0.49) | HSD17B2HSD17B1 | |
| SCHEMBL30164408 | 0.70 | ALDH1A1 (0.50) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116510-B | 2-substituted methylene dihydrobenzo [ d ] thiazole derivatives and synthesis method and application thereof | 华东师范大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-111116510-A | 2-substituted methylene dihydrobenzo [ d ] thiazole derivatives and synthesis method and application thereof | 华东师范大学 | 2020-05-08 | — | — | CN | disclosed |