Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19502636 | 0.86 | ROCK2 (0.41) | CTSBKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL24760246 | 0.82 | KMT2A (0.38) | KMT2AMEN1LMNAALDH1A1CA1 | |
| SCHEMBL22198532 | 0.82 | KMT2A (0.41) | KMT2AMEN1LMNAALDH1A1CA1 | |
| SCHEMBL19503127 | 0.80 | MAPT (0.41) | KMT2AMEN1LMNAALDH1A1DHODH | |
| SCHEMBL22990404 | 0.80 | ALDH1A1 (0.55) | KMT2AMEN1LMNAALDH1A1DHODH | |
| SCHEMBL2742150 | 0.79 | MEN1 (0.52) | KMT2AMEN1LMNAALDH1A1CA1 | |
| SCHEMBL12116549 | 0.78 | ALDH1A1 (0.45) | KMT2AALDH1A1CA1CA2MAPT | |
| SCHEMBL24164305 | 0.76 | LMNA (0.43) | KMT2AMEN1LMNAALDH1A1CA1 | |
| SCHEMBL22549263 | 0.76 | ALDH1A1 (0.55) | KMT2AMEN1LMNAALDH1A1DHODH | |
| SCHEMBL12026774 | 0.76 | CA1 (0.40) | KMT2AMEN1ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020056192-A1 | ANTIBODY CONJUGATES OF TOLL-LIKE RECEPTOR AGONISTS | SILVERBACK THERAPEUTICS, INC. (US) | 2020-03-19 | — | — | WO | disclosed |