Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.40 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.40 |
| ▸ | CTBP2 | P56545 | 7/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | KDM5C | P41229 | 4/20 | 0.37 |
| ▸ | KDM6B | O15054 | 2/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL304661 | 0.98 | EGLN1 (0.45) | EGLN1LMNAALKBH5SUCNR1MAPK1 | |
| SCHEMBL3467696 | 0.90 | LDHA (0.44) | CTBP2KDM4ELDHASRR | |
| SCHEMBL7763978 | 0.90 | LDHA (0.44) | CTBP2KDM4ELDHASRR | |
| SCHEMBL7824361 | 0.82 | LMNA (0.50) | EGLN1LMNAALKBH5SUCNR1MAPK1 | |
| SCHEMBL7824359 | 0.82 | LMNA (0.50) | EGLN1LMNAALKBH5SUCNR1MAPK1 | |
| Oxaloacetate SCHEMBL5614074 | 0.71 | EGLN1 (0.67) | EGLN1LMNAALKBH5SUCNR1MAPK1 | |
| Succinic Acid SCHEMBL812815 | 0.69 | EGLN1 (0.75) | EGLN1LMNAALKBH5SUCNR1MAPK1 | |
| Succinic Acid SCHEMBL1235179 | 0.69 | EGLN1 (0.75) | EGLN1LMNAALKBH5SUCNR1MAPK1 | |
| Succinic Acid SCHEMBL2222412 | 0.69 | LMNA (0.90) | EGLN1LMNAALKBH5SUCNR1MAPK1 | |
| Succinic Acid SCHEMBL8141952 | 0.69 | LMNA (0.90) | EGLN1LMNAALKBH5SUCNR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877699-B2 | Dishwasher detergent comprising a liquid non-ionic surfactant and at least two solid non-ionic surfactants | RECKITT & COLMAN (OVERSEAS) LIMITED (GB) | 2014-11-04 | — | — | US | claimed |
| EP-2449072-B1 | COMPOSITIONS | RECKITT BENCKISER NV (NL) | 2013-05-01 | — | — | EP | claimed |
| US-20120125374-A1 | Compositions | RECKITT BENCKISER N.V. (NL) | 2012-05-24 | — | — | US | claimed |
| EP-2449072-A1 | COMPOSITIONS | Reckitt Benckiser N.V. (NL) | 2012-05-09 | — | — | EP | claimed |
| WO-2011001170-A1 | COMPOSITIONS | RECKITT BENCKISER N.V. (NL) | 2011-01-06 | — | — | WO | claimed |
| JP-9100497-A | — | — | None | — | — | JP | disclosed |
| EP-4150037-B1 | SOLID COMPOSITION | RECKITT BENCKISER FINISH BV (NL) | 2025-11-26 | — | — | EP | disclosed |
| CN-111929998-B | Toner and method for producing toner | 佳能株式会社 | 2024-12-03 | — | — | CN | disclosed |
| CN-115551981-B | Solid composition | 雷克特本克斯尔菲尼施公司 | 2024-08-06 | — | — | CN | disclosed |
| WO-2024133097-A1 | LIQUID RINSE AID COMPOSITIONS | RECKITT BENCKISER FINISH B.V. (NL) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024133098-A1 | RINSE AID | RECKITT BENCKISER FINISH B.V. (NL) | 2024-06-27 | — | — | WO | disclosed |
| US-11851632-B2 | Solid composition comprising an ethoxylated alcohol with from 30 to 40 ethoxy groups | RECKITT BENCKISER FINISH B.V. (NL) | 2023-12-26 | — | — | US | disclosed |
| WO-2013064811-A1 | STABLE AQUEOUS PAP SUSPENSION | RECKITT BENCKISER N.V. (NL) | 2013-05-10 | — | — | WO | disclosed |
| EP-2449072-B1 | COMPOSITIONS | RECKITT BENCKISER NV (NL) | 2013-05-01 | — | — | EP | disclosed |
| WO-2012131390-A2 | DETERGENT COMPOSITION | RECKITT BENCKISER N.V. (NL) | 2012-10-04 | — | — | WO | disclosed |
| US-20120125374-A1 | Compositions | RECKITT BENCKISER N.V. (NL) | 2012-05-24 | — | — | US | disclosed |
| EP-2449072-A1 | COMPOSITIONS | Reckitt Benckiser N.V. (NL) | 2012-05-09 | — | — | EP | disclosed |
| WO-2012025740-A1 | DETERGENT COMPOSITION COMPRISING MANGANESE-OXALATE | RECKITT BENCKISER N.V. (NL) | 2012-03-01 | — | — | WO | disclosed |
| WO-2011001170-A1 | COMPOSITIONS | RECKITT BENCKISER N.V. (NL) | 2011-01-06 | — | — | WO | disclosed |
| JP-H09100497-A | PRODUCTION OF HIGH-BULK DENSITY DETERGENT COMPOSITION | LION CORP | 1997-04-15 | — | — | JP | disclosed |