Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.75 |
| ▸ | LMNA | P02545 | 5/20 | 0.75 |
| ▸ | LDHA | P00338 | 1/20 | 0.75 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.75 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.75 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.75 |
| ▸ | PHF8 | Q9UPP1 | 6/20 | 0.56 |
| ▸ | KDM2A | Q9Y2K7 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | KDM5C | P41229 | 4/20 | 0.56 |
| ▸ | KDM6B | O15054 | 2/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.53 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL1235179 | 1.00 | EGLN1 (0.75) | EGLN1LMNALDHASRRALKBH5 | |
| Malonic Acid SCHEMBL336 | 0.87 | — | — | |
| Succinic Acid SCHEMBL21867134 | 0.87 | LMNA (1.00) | EGLN1LMNALDHASRRALKBH5 | |
| Succinic Acid SCHEMBL3799615 | 0.87 | — | — | |
| Succinic Acid SCHEMBL24696 | 0.87 | LMNA (1.00) | EGLN1LMNALDHASRRALKBH5 | |
| Malonic Acid SCHEMBL1332554 | 0.87 | — | — | |
| Malonic Acid SCHEMBL1332587 | 0.87 | — | — | |
| Malonic Acid SCHEMBL1332405 | 0.87 | — | — | |
| Succinic Acid SCHEMBL4269135 | 0.87 | LMNA (1.00) | EGLN1LMNALDHASRRALKBH5 | |
| Malonic Acid SCHEMBL3358611 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 421 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4250922-A1 | SURFACE MODIFICATION TO REGULATE PLANT GROWTH | Bind-X GmbH (DE) | 2023-10-04 | — | — | EP | claimed |
| WO-2022111788-A1 | SURFACE MODIFICATION TO REGULATE PLANT GROWTH | Bind-X GmbH (DE) | 2022-06-02 | — | — | WO | claimed |
| WO-2014141181-A1 | PROCESS FOR PREPARING PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY NO 2 LIMITED (GB) | 2014-09-18 | — | — | WO | claimed |
| EP-1945717-A4 | HIGH LINOLENIC LINSEED OIL COMPOSITIONS | PETERSON LILLIAN (CA) | 2009-05-13 | — | — | EP | claimed |
| EP-1945717-A1 | HIGH LINOLENIC LINSEED OIL COMPOSITIONS | Peterson, Lillian (CA) | 2008-07-23 | — | — | EP | claimed |
| WO-2007051302-A1 | HIGH LINOLENIC LINSEED OIL COMPOSITIONS | PETERSON LILLIAN (CA) | 2007-05-10 | — | — | WO | claimed |
| US-20060165640-A1 | Cosmetic composition comprising at least one alkoxylated alcohol ester and at least one apolar oil | L'OREAL S.A. (FR) | 2006-07-27 | — | — | US | claimed |
| EP-0647184-B1 | BIODEGRADABLE, LIQUID IMPERVIOUS MULTILAYER FILM COMPOSITIONS | PROCTER & GAMBLE (US) | 1998-03-11 | — | — | EP | claimed |
| EP-0404876-B1 | LONG-CHAIN ALIPHATIC HYDROCARBYL AMINE ADDITIVES HAVING AN OXY-CARBONYL CONNECTING GROUP | CHEVRON RES & TECH (US) | 1995-02-15 | — | — | EP | claimed |
| US-3952049-A | EXO-TRIMETHYLENENORBORNYL, OILING AGENTS | KAO SOAP CO., LTD. (JA) | 1976-04-20 | — | — | US | claimed |
| WO-2024073576-A1 | 4-((2-(3,5-DICHLOROPHENYL)-6-((PYRIMIDIN-5-YL)OXY)PYRIDIN-4-YL)METHYL)PIPERAZINE DERIVATIVES AS FURIN INHIBITORS AND USES THEREOF | BP ASSET V, INC. (US) | 2024-04-04 | — | — | WO | disclosed |
| US-20240108620-A1 | Treatment Regimen | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2024-04-04 | — | — | US | disclosed |
| CN-111868071-B | Novel dopamine precursors | 耶路撒冷希伯来大学伊森姆研究发展有限公司 | 2024-03-26 | — | — | CN | disclosed |
| US-20240066133-A1 | THERAPEUTIC AGENTS AND CONJUGATES THEREOF | AJ SCIENCES (YIXING) CO., LTD (CN) | 2024-02-29 | — | — | US | disclosed |
| EP-3993796-B1 | COMBINATION FOR THE TREATMENT OF INFECTIONS CAUSED BY MYCOPLASMA GENITALIUM | GLAXOSMITHKLINE IP DEV LTD (GB) | 2024-02-21 | — | — | EP | disclosed |
| EP-0195846-A2 | Photo-curable epoxy resin type composition and curing process | KABUSHIKI KAISHA TOSHIBA (JP) | 1986-10-01 | — | — | EP | disclosed |
| US-4528360-A | Water-soluble film or sheet | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1985-07-09 | — | — | US | disclosed |
| EP-0123842-A1 | Photo-curable epoxy resin type composition | KABUSHIKI KAISHA TOSHIBA (JP) | 1984-11-07 | — | — | EP | disclosed |
| EP-0114258-A1 | Resin encapsulation type photo-semiconductor devices | KABUSHIKI KAISHA TOSHIBA (JP) | 1984-08-01 | — | — | EP | disclosed |
| EP-0015673-B1 | 3-AMINO-4-HOMOISOTWISTANE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-12-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240108620-A1 | Treatment Regimen | GNAQ, GMPS, GNPDA1 | EGLN1 2650/4885LMNA 3970/4885LDHA 2573/4885 |
| US-20060165640-A1 | Cosmetic composition comprising at least one alkoxylated alcohol ester and at least one apolar oil | CUTA, KRT18, ALK | EGLN1 1298/4885LMNA 584/4885LDHA 738/4885 |
| US-20240066133-A1 | THERAPEUTIC AGENTS AND CONJUGATES THEREOF | TLR9, STING1, TLR3 | EGLN1 3427/4885LMNA 1780/4885LDHA 4461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.