SCHEMBL21863151

SCHEMBL21863151

c1ccc(-c2ccc3c4ccc5ccccc5c4n(-c4ccc(-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)cc4)c3c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AVPR1A P37288 1/20 0.36
PDPK1 O15530 3/20 0.36
MAPT P10636 3/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
HSP90AA1 P07900 1/20 0.36
NR3C1 P04150 1/20 0.36
CYP1A1 P04798 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP1B1 Q16678 1/20 0.36
NPC1 O15118 1/20 0.35
LMNA P02545 1/20 0.35
RECQL P46063 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
RXRA P19793 1/20 0.34
ATM Q13315 1/20 0.34
OXTR P30559 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22483185 0.95 AVPR1A (0.39) AVPR1APDPK1MAPTMEN1KMT2A
SCHEMBL22483154 0.93 KDM4E (0.38) AVPR1APDPK1MAPTMEN1KMT2A
SCHEMBL24361334 0.93 PIK3CD (0.37) PDPK1MEN1KMT2ANR3C1CYP1A2
SCHEMBL17943440 0.92 L3MBTL1 (0.42) AVPR1APDPK1MAPTMEN1KMT2A
SCHEMBL17943405 0.92 L3MBTL1 (0.42) AVPR1APDPK1MAPTMEN1KMT2A
SCHEMBL25140465 0.92 L3MBTL1 (0.42) AVPR1APDPK1MAPTMEN1KMT2A
SCHEMBL21524323 0.92 L3MBTL1 (0.42) AVPR1APDPK1MAPTMEN1KMT2A
SCHEMBL17943425 0.92 L3MBTL1 (0.42) AVPR1APDPK1MAPTMEN1KMT2A
SCHEMBL24361935 0.91 KDM4E (0.37) PDPK1MAPTNR3C1CYP1A1CYP1A2
SCHEMBL24151793 0.91 KDM4E (0.37) PDPK1MAPTMEN1KMT2ANR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11758802-B2 Composition and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-09-12 US disclosed
US-11758802-B2 Composition and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-09-12 US disclosed
US-20210328149-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2021-10-21 US disclosed
US-20210184128-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-06-17 US disclosed
US-20200313095-A1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-10-01 US disclosed
US-20200176685-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2020-06-04 US disclosed
US-20200144508-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2020-05-07 US disclosed
US-20200144510-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2020-05-07 US disclosed
US-20200111967-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2020-04-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200144508-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OCIAD1, OCIAD2, OR10J3 AVPR1A 2744/4885PDPK1 2155/4885MAPT 2375/4885
US-20200313095-A1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CYBA AVPR1A 2716/4885PDPK1 4110/4885MAPT 497/4885
US-20210184128-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD1, OXER1 AVPR1A 2543/4885PDPK1 1950/4885MAPT 2317/4885
US-11758802-B2 Composition and organic light-emitting device including the same CRY1, CRY2, CYBA AVPR1A 2716/4885PDPK1 4110/4885MAPT 497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.