Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 5/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | F9 | P00740 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16202014 | 0.82 | ALDH1A1 (0.45) | RXRAGRIN1GRIN2BMGLLACHE | |
| SCHEMBL20260648 | 0.82 | KAT7 (0.35) | F9F10CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL16202012 | 0.79 | NOTUM (0.47) | NOTUMMGLLKMT2A | |
| SCHEMBL7127572 | 0.79 | MAPT (0.49) | KMT2A | |
| SCHEMBL30186345 | 0.79 | FGFR1 (0.44) | ACHEKMT2A | |
| SCHEMBL18278129 | 0.79 | KEAP1 (0.47) | KEAP1RXRAGRIN1GRIN2BNOTUM | |
| SCHEMBL18278660 | 0.79 | KEAP1 (0.47) | KEAP1RXRAGRIN1GRIN2BNOTUM | |
| SCHEMBL10360328 | 0.79 | KEAP1 (0.47) | KEAP1RXRAGRIN1GRIN2BNOTUM | |
| SCHEMBL23976857 | 0.79 | KEAP1 (0.47) | KEAP1RXRAGRIN1GRIN2BNOTUM | |
| SCHEMBL21849281 | 0.79 | KEAP1 (0.44) | KEAP1RXRAGRIN1GRIN2BNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065614-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |