Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PDE2A | O00408 | 11/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21849087 | 0.82 | KDM4E (0.59) | KDM4EPDE2ATSHRMGLLPLAT | |
| SCHEMBL21816299 | 0.80 | MGLL (0.46) | KDM4ETSHRMGLLPLATUSP2 | |
| SCHEMBL16421204 | 0.76 | KDM4E (0.50) | KDM4EPDE2ATSHR | |
| SCHEMBL21849273 | 0.76 | KDM4E (0.33) | KDM4EPDE2ATSHRMGLLPLAT | |
| SCHEMBL18781146 | 0.73 | PDE2A (0.39) | KDM4EPDE2AMAPT | |
| SCHEMBL5270607 | 0.72 | PIK3CG (0.68) | KDM4ETSHRPIK3CGMAPT | |
| SCHEMBL18780810 | 0.72 | PDE2A (0.38) | KDM4EPDE2AMAPT | |
| SCHEMBL1934247 | 0.71 | RAB9A (0.46) | KDM4E | |
| SCHEMBL737903 | 0.71 | SMN1; SMN2 (0.35) | KDM4EPDE2ATSHRPLAT | |
| SCHEMBL12305595 | 0.70 | PDE2A (0.43) | KDM4EPDE2ATSHRPIK3CGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065614-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |