Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3861449 | 0.77 | MAPT (0.41) | SMN1; SMN2NPC1RAB9AHPGDMAPT | |
| SCHEMBL8997500 | 0.75 | NPC1 (0.38) | SMN1; SMN2NPC1RAB9AHPGDMAPT | |
| SCHEMBL9154800 | 0.72 | SMN1; SMN2 (0.36) | SMN1; SMN2NPC1RAB9AHPGDMAPT | |
| SCHEMBL31548632 | 0.72 | NPC1 (0.33) | SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL1009010 | 0.67 | MAPT (0.36) | SMN1; SMN2NPC1RAB9AHPGDMAPT | |
| SCHEMBL31548634 | 0.66 | SIGMAR1 (0.44) | ATMCYP3A4SIGMAR1DRD2L3MBTL1 | |
| SCHEMBL574986 | 0.65 | NPSR1 (0.38) | SMN1; SMN2NPC1RAB9AHPGDMAPT | |
| SCHEMBL666883 | 0.65 | MAPT (0.37) | SMN1; SMN2NPC1RAB9AHPGDMAPT | |
| SCHEMBL1007069 | 0.64 | MAPT (0.39) | SMN1; SMN2NPC1RAB9AHPGDMAPT | |
| Iodide SCHEMBL3820109 | 0.64 | MAPT (0.36) | SMN1; SMN2NPC1RAB9AHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3637490-A1 | HIGH EFFICIENCY YELLOW LIGHT EMITTERS FOR OLED DEVICES | Universal Display Corporation (US) | 2020-04-15 | — | — | EP | disclosed |