SCHEMBL1007069

SCHEMBL1007069

C1=CN(c2ccccc2)CN1c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
SIGMAR1 Q99720 2/20 0.39
HPGD P15428 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HTR3E A5X5Y0 1/20 0.37
HTR3B O95264 1/20 0.37
ADRB1 P08588 1/20 0.37
HTR3A P46098 1/20 0.37
HTR3D Q70Z44 1/20 0.37
HTR3C Q8WXA8 1/20 0.37
LMNA P02545 1/20 0.37
CYP3A4 P08684 2/20 0.36
MAPK1 P28482 2/20 0.35
HTT P42858 1/20 0.35
KDM4E B2RXH2 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL30903858 0.97 MAPT (0.38) MAPTNPSR1MEN1KMT2ANPC1
Hydrochloric Acid SCHEMBL1156365 0.97 SMN1; SMN2 (0.41) MAPTNPSR1MEN1KMT2ANPC1
SCHEMBL28424843 0.90 MAPT (0.34) MAPTNPSR1MEN1KMT2ANPC1
SCHEMBL16429033 0.88 MAPT (0.50) MAPTNPSR1MEN1KMT2ANPC1
SCHEMBL5577143 0.86 FAAH (0.34) MAPTNPSR1MEN1KMT2ANPC1
Acetic Acid SCHEMBL28557579 0.86 NOTUM (0.40) MEN1KMT2ASMN1; SMN2LMNAMAPK1
SCHEMBL666883 0.83 MAPT (0.37) MAPTNPSR1MEN1KMT2ANPC1
Iodide SCHEMBL28360230 0.81 MAPT (0.36) MAPTNPSR1MEN1KMT2ANPC1
Iodide SCHEMBL3820109 0.81 MAPT (0.36) MAPTNPSR1MEN1KMT2ANPC1
Hydrochloric Acid SCHEMBL384463 0.81 MAPT (0.36) MAPTNPSR1MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104549504-B A kind of NHC-metal-glyoxaline structure type catalyst and preparation method thereof 中国石油化工股份有限公司 2017-01-04 CN claimed
CN-104549504-A NHC-metal-imidazole structured catalyst and preparation method thereof CHINA PETROLEUM & CHEMICAL 2015-04-29 CN claimed
US-12291506-B2 Method for producing amidate compound, and amidate compound KOEI CHEMICAL COMPANY, LIMITED (JP) 2025-05-06 US disclosed
CN-119263997-A Method for synthesizing yield-increasing amine by visible light induction 河南省科学院高新技术研究中心 2025-01-07 CN disclosed
CN-118290346-A Method for producing amide compound, and amide compound 广荣化学株式会社 2024-07-05 CN disclosed
CN-112703184-B Method for producing amide compound, and amide compound 广荣化学株式会社 2024-06-11 CN disclosed
US-11827651-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
CN-114213468-B Iridium complex and application thereof in yield-increasing amine synthesis 河南省科学院高新技术研究中心 2023-11-03 CN disclosed
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 US disclosed
US-20230320188-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-20230309374-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 US disclosed
US-20040143138-A1 Process for the preparation of nitrodiphenylamines LANXESS DEUTSCHLAND GMBH (DE) 2004-07-22 US disclosed
EP-1437341-A1 Process for the preparation of nitrodiphenylamines Bayer Aktiengesellschaft (DE) 2004-07-14 EP disclosed
US-20040133004-A1 Rhodium and iridium complexes MERCK PATENT GMBH (DE) 2004-07-08 US disclosed
US-20030050406-A1 Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization ZEON CORPORATION 2003-03-13 US disclosed
US-20030018138-A1 Copolymer formed by ring -opening polymerization, product of hydrogenation of copolymer formed by ring-opening polymerization, and process for producing these ZEON CORPORATION (JP) 2003-01-23 US disclosed
EP-1275675-A1 COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, PRODUCT OF HYDROGENATION OF COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, AND PROCESSES FOR PRODUCING THESE Zeon Corporation (JP) 2003-01-15 EP disclosed
US-6486264-B1 Process for producing hydrogenated ring-opening polymerization polymer of cycloolefin ZEON CORPORATION (JP) 2002-11-26 US disclosed
EP-1197509-A1 PROCESS FOR PRODUCING HYDROGENATED RING-OPENING POLYMERIZATION POLYMER OF CYCLOOLEFIN Nippon Zeon Co., Ltd. (JP) 2002-04-17 EP disclosed
US-5001196-A Process for preparation of diene type polymer rubber NIPPON ZEON CO., LTD. (JP) 1991-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309374-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, LBR, SSB MAPT 3611/4885NPSR1 1467/4885MEN1 2173/4885
US-12291506-B2 Method for producing amidate compound, and amidate compound NAAA, NIT2, PAM MAPT 2416/4885NPSR1 2439/4885MEN1 55/4885
US-20230320188-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, MLX MAPT 3664/4885NPSR1 1670/4885MEN1 2650/4885
US-20040143138-A1 Process for the preparation of nitrodiphenylamines HNMT, PNMT, NNMT MAPT 1465/4885NPSR1 399/4885MEN1 1431/4885
US-20040133004-A1 Rhodium and iridium complexes RPIA, SIRT5, INPP5B MAPT 2358/4885NPSR1 2321/4885MEN1 453/4885
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, OCIAD1, LBR MAPT 3040/4885NPSR1 2620/4885MEN1 3573/4885
US-11827651-B2 Organic electroluminescent materials and devices SSB, L1CAM, LEF1 MAPT 2286/4885NPSR1 2365/4885MEN1 2446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.