SCHEMBL574986

SCHEMBL574986

C1=NCN(c2ccccc2)CN1c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.38
MAPT P10636 5/20 0.37
LMNA P02545 2/20 0.37
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
HPGD P15428 2/20 0.37
SIGMAR1 Q99720 2/20 0.36
HTR3E A5X5Y0 1/20 0.36
HTR3B O95264 1/20 0.36
ADRB1 P08588 1/20 0.36
HTR3A P46098 1/20 0.36
HTR3D Q70Z44 1/20 0.36
HTR3C Q8WXA8 1/20 0.36
CHRNA7 P36544 3/20 0.34
NFKB1 P19838 2/20 0.34
CYP3A4 P08684 1/20 0.34
ALOX15 P16050 1/20 0.34
CHRNB2 P17787 1/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9154800 0.78 SMN1; SMN2 (0.36) NPSR1MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL28053371 0.78 NPC1 (0.36) NPSR1MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL30015050 0.78 HTR7 (0.34) MAPTHPGDMAPK1ALDH1A1KDM4E
SCHEMBL2544304 0.74 MAPT (0.50) MAPTLMNASMN1; SMN2ADRB1MEN1
SCHEMBL4889715 0.74 MAPT (0.41) NPSR1MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL9728352 0.69 SMN1; SMN2 (0.40) NPSR1MAPTLMNASMN1; SMN2HPGD
SCHEMBL28318763 0.68 LMNA (0.40) NPSR1MAPTLMNANPC1RAB9A
SCHEMBL105023 0.68 SIGMAR1 (0.41) NPSR1MAPTLMNANPC1RAB9A
SCHEMBL6272216 0.68 SIGMAR1 (0.41) NPSR1MAPTLMNANPC1RAB9A
SCHEMBL9728456 0.68 TDP1 (0.35) NPSR1MAPTLMNASIGMAR1CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8455598-B2 Production of elastomeric functionalized olefin polymers EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2013-06-04 US claimed
US-20120322948-A1 PRODUCTION OF ELASTOMERIC FUNCTIONALIZED OLEFIN POLYMERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2012-12-20 US claimed
US-20100317463-A1 GOLF BALLS HAVING LAYERS MADE FROM FUNCTIONALIZED ETHYLENE COPOLYMERS ACUSHNET COMPANY 2010-12-16 US claimed
US-7504465-B2 Linear functional copolymers of ethylene with precise and minimum run length distributions and methods of making thereof EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2009-03-17 US claimed
US-20090062475-A1 Production of elastomeric functionalized olefin polymers EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2009-03-05 US claimed
US-20080312393-A1 Linear functional copolymers of ethylene with precise and minimum run length distributions and methods of making thereof BAUGH LISA S 2008-12-18 US claimed
EP-1704172-A1 LINEAR FUNCTIONAL COPOLYMERS OF ETHYLENE WITH PRECISE AND MINIMUM RUN LENGTH DISTRIBUTIONS AND METHODS OF MAKING THEREOF ExxonMobil Research and Engineering Company (US) 2006-09-27 EP claimed
WO-2005063834-A1 LINEAR FUNCTIONAL COPOLYMERS OF ETHYLENE WITH PRECISE AND MINIMUM RUN LENGTH DISTRIBUTIONS AND METHODS OF MAKING THEREOF EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2005-07-14 WO claimed
US-20050137369-A1 Linear functional copolymers of ethylene with precise and minimum run length distributions and method of making thereof EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2005-06-23 US claimed
US-4322260-A Process for the continuous extrusion forming of a plastic double-walled foam-core conduit MONSANTO COMPANY (US) 1982-03-30 US claimed
US-4279815-A DIAZOTIZATION, COUPLING HERKES FRANK E 1981-07-21 US claimed
EP-4559993-A1 PRODUCTION OF RUBBER COMPOSITIONS FROM END OF LIFE TIRES The Goodyear Tire & Rubber Company (US) 2025-05-28 EP disclosed
US-20250163236-A1 PRODUCTION OF RUBBER COMPOSITIONS FROM END OF LIFE TIRES THE GOODYEAR TIRE & RUBBER COMPANY 2025-05-22 US disclosed
WO-2025023320-A1 GASKET MEMBER 大日本印刷株式会社 2025-01-30 WO disclosed
US-20240124683-A1 RUBBER - FORMING ADDITIVES FROM BIOMASS THROUGH SYNGAS PRODUCTION THE GOODYEAR TIRE & RUBBER COMPANY 2024-04-18 US disclosed
US-4279815-A DIAZOTIZATION, COUPLING HERKES FRANK E 1981-07-21 US disclosed
US-4232106-A Photosensitive compositions containing 2-halomethyl-5-vinyl-1,3,4-oxadiazoles as free radical progenitors FUJI PHOTO FILM CO., LTD. (JP) 1980-11-04 US disclosed
US-3966595-A REVERSE OSMOSIS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-06-29 US disclosed
US-3950198-A FUSION OF VINYL PLASTISOL TO HEAT-SENSITIVE BACKING MONSANTO COMPANY (US) 1976-04-13 US disclosed
US-3932296-A AMMONIA DERIVATIVE, QUARTERNARY AMMONIUM COMPOUND THE DOW CHEMICAL COMPANY (US) 1976-01-13 US disclosed