SCHEMBL21864347

SCHEMBL21864347

Cc1cccnc1-c1ccccc1C1C=CC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 1/20 0.40
TNKS2 Q9H2K2 1/20 0.39
CYP2A6 P11509 1/20 0.38
GAA P10253 1/20 0.38
METAP2 P50579 1/20 0.36
HTR1A P08908 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
OPRL1 P41146 1/20 0.34
PTPRC P08575 2/20 0.34
CTSL P07711 1/20 0.34
CTSS P25774 1/20 0.34
PTPN13 Q12923 1/20 0.34
NISCH Q9Y2I1 1/20 0.34
KMT2A Q03164 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C19 P33261 1/20 0.34
PDK2 Q15119 1/20 0.34
TDP2 O95551 1/20 0.33
NSD2 O96028 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21565051 0.76 PTGS2 (0.43) ADRA1ATNKS2CYP2A6GAAHTR1A
SCHEMBL24041236 0.76 GAA (0.41) ADRA1ATNKS2CYP2A6GAAMETAP2
SCHEMBL18729720 0.74 KDM4E (0.43) ADRA1ANISCHKMT2ACYP1A2PDK2
SCHEMBL4160810 0.74 CYP2A6 (0.52) ADRA1ACYP2A6GAAMETAP2PTPRC
SCHEMBL2322176 0.71 CHRNB2 (0.42) ADRA1ATNKS2CYP2A6HTR1ASLC6A2
SCHEMBL22883855 0.71 CYP2A6 (0.48) ADRA1ACYP2A6GAAMETAP2PTPRC
SCHEMBL21033797 0.69 ALDH1A1 (0.50) CYP2A6GAAMETAP2NISCH
SCHEMBL3423330 0.69 CYP2A6 (0.50) ADRA1ACYP2A6GAAMETAP2PTPRC
SCHEMBL16547422 0.68 ALDH1A1 (0.46) ADRA1ACYP2A6GAAMETAP2PTPRC
SCHEMBL10100787 0.68 CYP2A6 (0.55) ADRA1ACYP2A6GAAMETAP2PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3637490-A1 HIGH EFFICIENCY YELLOW LIGHT EMITTERS FOR OLED DEVICES Universal Display Corporation (US) 2020-04-15 EP disclosed