Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21864643 | 0.90 | HPGD (0.43) | HPGDALDH1A1KDM4ELMNAABCB1 | |
| SCHEMBL21864570 | 0.83 | CHEK2 (0.47) | HPGDALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL3044200 | 0.76 | L3MBTL1 (0.68) | HPGDALDH1A1LMNAKMT2AUSP2 | |
| SCHEMBL3053864 | 0.76 | L3MBTL1 (0.68) | HPGDALDH1A1LMNAKMT2AUSP2 | |
| SCHEMBL28855980 | 0.76 | L3MBTL1 (0.68) | HPGDALDH1A1LMNAKMT2AUSP2 | |
| SCHEMBL21830613 | 0.71 | HPGD (0.37) | HPGDALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL21864574 | 0.70 | PARP15 (0.56) | HPGDALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL9192112 | 0.70 | MAOB (0.62) | HPGDALDH1A1KDM4EKMT2AALDH2 | |
| SCHEMBL27582367 | 0.70 | CA12 (0.58) | HPGDALDH1A1KDM4EKMT2AALDH2 | |
| SCHEMBL8672706 | 0.70 | L3MBTL1 (0.78) | HPGDALDH1A1LMNARAB9ARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020071550-A1 | CDK8 INHIBITOR AND USE OF SAME | 京都薬品工業株式会社 | 2020-04-09 | — | — | WO | disclosed |