Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21864575 | 0.90 | HPGD (0.46) | HPGDALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL21864738 | 0.78 | NR4A2 (0.38) | HPGDALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL21864570 | 0.76 | CHEK2 (0.47) | HPGDALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL21864684 | 0.69 | CHEK2 (0.41) | CYP2C9RARB | |
| SCHEMBL21830613 | 0.69 | HPGD (0.37) | HPGDALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL21864574 | 0.67 | PARP15 (0.56) | HPGDALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL8672706 | 0.67 | L3MBTL1 (0.78) | HPGDALDH1A1LMNARAB9APOLB | |
| SCHEMBL15842690 | 0.67 | NPC1 (0.56) | ALDH1A1KDM4EKMT2ARAB9ANPC1 | |
| SCHEMBL8114039 | 0.67 | PIM1 (0.58) | HPGDALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL21864737 | 0.66 | NOD2 (0.44) | HPGDALDH1A1KDM4ELMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020071550-A1 | CDK8 INHIBITOR AND USE OF SAME | 京都薬品工業株式会社 | 2020-04-09 | — | — | WO | disclosed |