SCHEMBL218652

SCHEMBL218652

O=C(c1[c]cccc1)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.54
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
ATM Q13315 1/20 0.46
SRD5A2 P31213 1/20 0.46
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
AKR1C3 P42330 1/20 0.43
CES2 O00748 2/20 0.42
CES1 P23141 2/20 0.42
TSHR P16473 2/20 0.42
DAO P14920 1/20 0.42
NAPRT Q6XQN6 1/20 0.42
MAPT P10636 3/20 0.41
RAB9A P51151 2/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
MAPK13 O15264 1/20 0.41
MAPK12 P53778 1/20 0.41
MAPK11 Q15759 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL29275067 0.98 ALDH1A1 (0.52) ALDH1A1TDP1L3MBTL1ATMSRD5A2
SCHEMBL143892 0.86 ALDH1A1 (0.38) ALDH1A1TDP1L3MBTL1ATMSRD5A2
SCHEMBL8372122 0.86 LMNA (0.52) ALDH1A1TDP1L3MBTL1SRD5A2KMT2A
SCHEMBL7525114 0.84 LTA4H (0.44) ALDH1A1KMT2AMEN1CES2CES1
SCHEMBL5847128 0.84 NR4A1 (0.49) ALDH1A1L3MBTL1SRD5A2CES2CES1
SCHEMBL6838248 0.84 AKR1C3 (0.49) L3MBTL1KMT2AMEN1AKR1C3CES2
SCHEMBL315202 0.84 ALDH1A1 (0.54) ALDH1A1TDP1ATMSRD5A2KMT2A
SCHEMBL8616020 0.81 ALDH1A1 (0.34) ALDH1A1TDP1L3MBTL1ATMSRD5A2
SCHEMBL14855785 0.80 PARP1 (0.49) ALDH1A1TDP1L3MBTL1ATMKMT2A
SCHEMBL3236378 0.80 ALDH1A1 (0.50) ALDH1A1TDP1KMT2AMEN1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2020 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4341314-A1 AMINE-SUBSTITUTED PYRROLIDINE-2,5-DIONYL COPOLYMERS, POLYIMIDES, ARTICLES, AND METHODS Essex Furukawa Magnet Wire USA LLC (US) 2024-03-27 EP claimed
US-20240093039-A1 WOOD-PRESERVING TREATMENT SOLUTION AND METHOD FOR PRODUCING WOOD PROVIDED WITH WOOD PRESERVATIVE AGC Inc. (JP) 2024-03-21 US claimed
US-20230301303-A1 A STORAGE STABLE INSECTICIDAL COMPOSITION UPL LTD (IN) 2023-09-28 US claimed
US-11702571-B2 Adhesive sheet for temporary fixation and method of manufacturing semiconductor device using the same LG CHEM, LTD. (KR) 2023-07-18 US claimed
CN-116239578-A Piperazine dione ring compound, synthesis method thereof and application thereof in preparation of antitumor drugs 中国海洋大学 2023-06-09 CN claimed
WO-2022271202-A9 AMINE-SUBSTITUTED PYRROLIDINE-2,5-DIONYL COPOLYMERS, POLYIMIDES, ARTICLES, AND METHODS ESSEX FURUKAWA MAGNET WIRE USA LLC (US) 2023-03-16 WO claimed
EP-3566863-B1 PHOTONIC CRYSTAL STRUCTURE AND ANTI-FORGERY COLOR CONVERSION FILM COMPRISING SAME KOREA RES INST CHEMICAL TECH (KR) 2023-03-08 EP claimed
WO-2022271338-A1 AMINE-SUBSTITUTED 2-AMINO-ETHAN-1-OLYL POLYMERS, POLYIMIDES, ARTICLES, AND METHODS ESSEX FURUKAWA MAGNET WIRE USA LLC (US) 2022-12-29 WO claimed
WO-2022271202-A1 AMINE-SUBSTITUTED PYRROLIDINE-2,5-DIONYL COPOLYMERS, POLYIMIDES, ARTICLES, AND METHODS ESSEX FURUKAWA MAGNET WIRE USA LLC (US) 2022-12-29 WO claimed
US-11531150-B2 Photonic crystal structure and anti-forgery color conversion film comprising same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2022-12-20 US claimed
US-4140681-A ANTICOAGULANTS MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1979-02-20 US claimed
US-4131673-A INHIBITION AND SUPPRESSION OF THROMBOSIS IN MAMMALS MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1978-12-26 US claimed
US-4128536-A ULTRAVIOLET LIGHT ABSORBERS GAF CORPORATION (US) 1978-12-05 US claimed
US-4125604-A PEPTIDES, ANTITHROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1978-11-14 US claimed
US-4101653-A ANTITHROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1978-07-18 US claimed
US-4097472-A INHIBITION AND SUPRESSION OF THROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1978-06-27 US claimed
US-4093712-A ANTITHROMBOGENIC AGENTS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1978-06-06 US claimed
US-4082749-A FROM CARBOXAMIDES AND ALKALI METAL HYPOCHLORITE, CATALYST BASF AKTIENGESELLSCHAFT (DT) 1978-04-04 US claimed
US-4066773-A ANTITHROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1978-01-03 US claimed
US-4022829-A INTERMEDIATES FOR SUNSCREEN AGENTS COLGATE-PALMOLIVE COMPANY (US) 1977-05-10 US claimed