SCHEMBL2186532

SCHEMBL2186532

CC(O)NC(=O)CCC(=O)NC(C)O

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.43
MEN1 O00255 1/20 0.43
MAPK1 P28482 1/20 0.43
KMT2A Q03164 1/20 0.43
ALDH1A1 P00352 1/20 0.41
HDAC3 O15379 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
PSMB5 P28074 1/20 0.36
CTSD P07339 1/20 0.36
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.34
ASAH2 Q9NR71 1/20 0.34
EPHX2 P34913 1/20 0.34
DNM1 Q05193 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15575426 0.90 PHF8 (0.48) ALDH1A1HDAC3HDAC1HDAC2HDAC8
SCHEMBL8621792 0.89
SCHEMBL7280161 0.88 ALDH1A1 (0.39) FAAHMEN1MAPK1KMT2AALDH1A1
SCHEMBL18422549 0.85
SCHEMBL8622266 0.83 FAAH (0.61) FAAHMEN1MAPK1KMT2AALDH1A1
SCHEMBL11197382 0.83 MEN1 (0.45) FAAHMEN1MAPK1KMT2AALDH1A1
SCHEMBL8621683 0.81 FAAH (0.70) FAAHMEN1MAPK1KMT2AALDH1A1
SCHEMBL11192290 0.80
SCHEMBL1129488 0.80
SCHEMBL8627798 0.79 FAAH (0.74) FAAHMEN1MAPK1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110213077-A1 Hydroquinone-containing polyesters having improved whiteness SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2011-09-01 US disclosed
US-20110204407-A1 Power LED device with a reflector made of aromatic polyester and/or wholly aromatic polyester SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2011-08-25 US disclosed
EP-2342255-A1 HYDROQUINONE-CONTAINING POLYESTERS HAVING IMPROVED WHITENESS Solvay Advanced Polymers, L.L.C. (US) 2011-07-13 EP disclosed
EP-2342766-A1 POWER LED DEVICE WITH A REFLECTOR MADE OF AROMATIC POLYESTER AND/OR WHOLLY AROMATIC POLYESTER Solvay Advanced Polymers, L.L.C. (US) 2011-07-13 EP disclosed
WO-2010049531-A1 POWER LED DEVICE WITH A REFLECTOR MADE OF AROMATIC POLYESTER AND/OR WHOLLY AROMATIC POLYESTER SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2010-05-06 WO disclosed
WO-2010049526-A1 HYDROQUINONE-CONTAINING POLYESTERS HAVING IMPROVED WHITENESS SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2010-05-06 WO disclosed
EP-1498442-B1 Method for the preparation of a polyester block copolymer composition DAICEL CHEM (JP) 2009-02-11 EP disclosed
US-7196123-B2 Polyester block copolymer composition and process for the preparation thereof WATANABE JUN 2007-03-27 US disclosed
EP-1498442-A2 Method for the preparation of a polyester block copolymer, a polyester block copolymer composition and method for the preparation thereof Daicel Chemical Industries, Ltd. (JP) 2005-01-19 EP disclosed
US-20040010092-A1 Method for the preparation of a polyester block copolymer, a polyester block copolymer composition and method for the preparation thereof WATANABE JUN (JP) 2004-01-15 US disclosed
US-6593434-B1 Condensation polymerization, esterification, melt mixing or kneading; high molecular weight, low crystallinity DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-07-15 US disclosed
EP-1120432-A1 PROCESS FOR THE PRODUCTION OF POLYESTER BLOCK COPOLYMERS, POLYESTER BLOCK COPOLYMER COMPOSITIONS AND PROCESS FOR THE PREPARATION THEREOF DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2001-08-01 EP disclosed
US-5631389-A SUCCINAMIDES WITH SUGAR GROUPS, POLLUTION CONTROL, BIODEGRADABLE LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-05-20 US disclosed