Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 18/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 18/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 18/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 18/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 18/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 18/20 | 0.45 |
| ▸ | AHCY | P23526 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21865614 | 0.92 | PSEN1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL21865620 | 0.90 | AHCY (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL21865632 | 0.90 | PSEN1 (0.45) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL21865619 | 0.82 | AHCY (0.40) | AHCY | |
| SCHEMBL21865763 | 0.82 | PSEN1 (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL21865761 | 0.80 | AHCY (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL21865383 | 0.77 | AHCY (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL21865385 | 0.76 | AHCY (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28368453 | 0.76 | PSEN1 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL21865570 | 0.75 | AHCY (0.40) | AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020052509-A1 | SULFONAMIDE COMPOUND SERVING AS SODIUM CHANNEL BLOCKER AND USES THEREOF | 成都康弘药业集团股份有限公司 | 2020-03-19 | — | — | WO | disclosed |