Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21865558 | 0.89 | ABL1 (0.40) | AHCYTSHRALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL28371791 | 0.88 | CYP3A4 (0.44) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL21865383 | 0.86 | AHCY (0.41) | AHCYTSHRALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL21865385 | 0.85 | AHCY (0.40) | AHCYTSHRALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL21865632 | 0.85 | PSEN1 (0.45) | AHCY | |
| SCHEMBL21865761 | 0.84 | AHCY (0.40) | AHCYTSHRALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL21865760 | 0.82 | AHCY (0.39) | AHCYTSHRALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL21865387 | 0.79 | ALDH1A1 (0.46) | AHCYALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL21865379 | 0.78 | NPSR1 (0.38) | AHCYSMN1; SMN2MEN1KMT2ACYP3A4 | |
| SCHEMBL21865763 | 0.77 | PSEN1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020052509-A1 | SULFONAMIDE COMPOUND SERVING AS SODIUM CHANNEL BLOCKER AND USES THEREOF | 成都康弘药业集团股份有限公司 | 2020-03-19 | — | — | WO | disclosed |