Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21865760 | 0.89 | AHCY (0.39) | AHCYALDH1A1LMNAMEN1HTT | |
| SCHEMBL21865636 | 0.82 | PSEN1 (0.45) | AHCY | |
| SCHEMBL21865620 | 0.81 | AHCY (0.41) | AHCYALDH1A1HCRTR1HCRTR2KDM4E | |
| SCHEMBL29835255 | 0.80 | ALDH1A1 (0.42) | AHCYALDH1A1LMNAMEN1HTT | |
| SCHEMBL21865672 | 0.80 | ALDH1A1 (0.42) | AHCYALDH1A1LMNAMEN1HTT | |
| SCHEMBL28364266 | 0.76 | ALDH1A1 (0.37) | ALDH1A1LMNAMEN1HTTKMT2A | |
| SCHEMBL21865383 | 0.75 | AHCY (0.41) | AHCYALDH1A1MEN1KMT2A | |
| SCHEMBL21865614 | 0.75 | PSEN1 (0.43) | AHCY | |
| SCHEMBL21865385 | 0.74 | AHCY (0.40) | AHCYALDH1A1AAK1 | |
| SCHEMBL21865632 | 0.74 | PSEN1 (0.45) | AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020052509-A1 | SULFONAMIDE COMPOUND SERVING AS SODIUM CHANNEL BLOCKER AND USES THEREOF | 成都康弘药业集团股份有限公司 | 2020-03-19 | — | — | WO | disclosed |