Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | FABP7 | O15540 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9356307 | 0.82 | ALDH1A1 (0.54) | FKBP1AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9352186 | 0.82 | ALDH1A1 (0.54) | FKBP1AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9352202 | 0.79 | FKBP1A (0.51) | FKBP1AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3718243 | 0.78 | ALDH1A1 (0.51) | ALDH1A1 | |
| SCHEMBL14754192 | 0.78 | ALDH1A1 (0.51) | ALDH1A1 | |
| SCHEMBL10258854 | 0.78 | ALDH1A1 (0.51) | ALDH1A1 | |
| SCHEMBL9083343 | 0.78 | ALDH1A1 (0.51) | ALDH1A1 | |
| SCHEMBL11106021 | 0.78 | ALDH1A1 (0.51) | ALDH1A1 | |
| SCHEMBL5466112 | 0.78 | ALDH1A1 (0.51) | ALDH1A1 | |
| SCHEMBL22388834 | 0.78 | FKBP1A (0.46) | FKBP1AALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020063388-A1 | SUBSTITUTED 5-OXOPYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 沈阳药科大学 | 2020-04-02 | — | — | WO | disclosed |