Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2187377 | 0.92 | CHRM4 (0.55) | ALDH1A1KDM4EKDM4CTDP1LMNA | |
| SCHEMBL2187462 | 0.89 | KDM4E (0.50) | ALDH1A1KDM4EKDM4CTDP1LMNA | |
| SCHEMBL2185882 | 0.87 | LMNA (0.60) | ALDH1A1LMNANPSR1HTTSMN1; SMN2 | |
| SCHEMBL2187544 | 0.87 | CHRM4 (0.50) | ALDH1A1KDM4EKDM4CTDP1LMNA | |
| SCHEMBL2187381 | 0.85 | STAT3 (0.48) | ALDH1A1KDM4EKDM4CTDP1LMNA | |
| SCHEMBL2187066 | 0.85 | LMNA (0.58) | ALDH1A1LMNANPSR1HTTSMN1; SMN2 | |
| SCHEMBL2188169 | 0.84 | LMNA (0.55) | ALDH1A1LMNANPSR1HTTSMN1; SMN2 | |
| SCHEMBL27756397 | 0.84 | LMNA (0.55) | ALDH1A1LMNANPSR1HTTSMN1; SMN2 | |
| SCHEMBL2188107 | 0.82 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNANPSR1HTT | |
| SCHEMBL2185460 | 0.82 | KMT2A (0.57) | ALDH1A1KDM4ELMNANPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343293-A1 | NOVEL PIPERIDIN-4-YL-THIAZOLE-CARBOXAMIDE ANALOGUES AS INHIBITORS OF T-CELL PROLIFERATION AND USES THEREOF | 4SC AG (DE) | 2011-07-13 | — | — | EP | disclosed |