Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.73 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.63 |
| ▸ | MMP1 | P03956 | 2/20 | 0.60 |
| ▸ | MMP2 | P08253 | 1/20 | 0.60 |
| ▸ | MMP3 | P08254 | 1/20 | 0.60 |
| ▸ | MMP7 | P09237 | 1/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | MMP13 | P45452 | 1/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MMP12 | P39900 | 1/20 | 0.55 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29134888 | 0.83 | ATM (0.59) | ATMKAT6AMMP2MMP9GAA | |
| SCHEMBL30015910 | 0.83 | ATM (0.59) | ATMKAT6AMMP2MMP9GAA | |
| SCHEMBL13330110 | 0.81 | APEX1 (0.54) | ATMMMP1MMP2MMP3MMP7 | |
| SCHEMBL359770 | 0.81 | MMP1 (0.79) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL18498633 | 0.80 | ATM (0.72) | ATMKAT6AKMT2AMEP1BTDP1 | |
| SCHEMBL30015741 | 0.79 | ATM (0.70) | ATMKAT6AKMT2AGAAMEP1B | |
| SCHEMBL1348672 | 0.79 | ATM (0.70) | ATMKAT6AKMT2AGAAMEP1B | |
| SCHEMBL29955316 | 0.78 | ALDH1A1 (0.60) | MMP1APEX1KMT2AGAAMMP12 | |
| SCHEMBL15721307 | 0.78 | APEX1 (0.54) | ATMMMP1MMP2MMP3MMP7 | |
| SCHEMBL17513498 | 0.78 | ATM (0.60) | ATMKAT6AKMT2ATDP1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200115357-A1 | LIVER X RECEPTORS (LXR) MODULATORS | PHENEX-FXR GMBH (DE) | 2020-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200115357-A1 | LIVER X RECEPTORS (LXR) MODULATORS | NR1H2, NR1H3, NR1H4 | ATM 3280/4885KAT6A 1519/4885MMP1 4830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.