SCHEMBL359770

SCHEMBL359770

O=C(O)CNS(=O)(=O)c1ccccc1

nearest known ligand 0.79

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 2/20 0.79
GAA P10253 1/20 0.79
MMP12 P39900 1/20 0.79
MMP2 P08253 1/20 0.64
MMP3 P08254 1/20 0.64
MMP7 P09237 1/20 0.64
MMP9 P14780 1/20 0.64
MMP13 P45452 1/20 0.64
KMT2A Q03164 1/20 0.63
TBXA2R P21731 1/20 0.59
ALDH1A1 P00352 1/20 0.59
APEX1 P27695 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL15012437 0.89 MMP1 (0.66) MMP1GAAMMP12MMP2MMP3
SCHEMBL10890150 0.89 MMP1 (1.00) MMP1GAAMMP12MMP2MMP3
SCHEMBL6762336 0.87 MMP1 (0.63) MMP1GAAMMP12MMP2MMP3
SCHEMBL2760714 0.87 MMP1 (0.61) MMP1GAAMMP12MMP2MMP3
SCHEMBL6802713 0.84 MMP1 (0.69) MMP1GAAMMP12MMP2MMP3
SCHEMBL8446048 0.84 MMP1 (0.69) MMP1GAAMMP12MMP2MMP3
SCHEMBL8446540 0.84 MMP1 (0.69) MMP1GAAMMP12MMP2MMP3
SCHEMBL8446539 0.84 MMP1 (0.69) MMP1GAAMMP12MMP2MMP3
SCHEMBL2969958 0.84 MMP1 (0.59) MMP1GAAMMP12MMP2MMP3
SCHEMBL10788040 0.84 MMP1 (0.59) MMP1GAAMMP12MMP2MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110177783-A Hormone receptor modulators for the treatment of metabolic conditions and disorders 阿德利克斯股份有限公司 2019-08-27 CN claimed
US-20130165446-A1 BENZO-OR PYRIDO-IMIDAZOLE DERIVATIVE HORIKOSHI, HIROYOSHI (CA) 2013-06-27 US claimed
EP-2581373-A1 BENZO- OR PYRIDO-IMIDAZOLE DERIVATIVE Fujita, Takashi (JP) 2013-04-17 EP claimed
CN-101180029-B Parakeratosis inhibitor, pore-shrinking agent or agent for preventing and improving rough skin, and composition for external use on skin SHISEIDO CO LTD 2011-02-16 CN claimed
US-20090215893-A1 Parakeratosis inhibitor, pore-shrinking agent,or rough skin preventing/ameliorating agent, and external composition for skin SHISEIDO COMPANY LTD (JP) 2009-08-27 US claimed
CN-101180029-A Parakeratosis inhibitor, pore-shrinking agent or agent for preventing and improving rough skin, and composition for external use on skin SHISEIDO CO LTD (JP) 2008-05-14 CN claimed
EP-1884230-A1 PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT OR AGENT FOR PREVENTING/AMELIORATING ROUGH SKIN AND EXTERNAL COMPOSITION FOR SKIN Shiseido Company, Limited (JP) 2008-02-06 EP claimed
US-20040063725-A1 Novel n(phenylsulphonyl)glycine derivatives and their therapeutic use LABORATORIES FOURNIER S.A. (FR) 2004-04-01 US claimed
CN-1484633-A N (phenylsulphonyl) glycine derivatives and their therapentic use ʵ���Ҹ���Ү��˾ 2004-03-24 CN claimed
EP-1351928-A2 NOVEL N(PHENYLSULPHONYL)GLYCINE DERIVATIVES AND THEIR THERAPEUTIC USE LABORATOIRES FOURNIER S.A. (FR) 2003-10-15 EP claimed
WO-2002053516-A2 N(PHENYLSULPHONYL)GLYCINE DERIVATIVES AND THEIR THERAPEUTIC USE LABORATOIRES FOURNIER SA (FR) 2002-07-11 WO claimed
CN-1045766-C N-aminoalkylcarbonyloxyalkylpyrrole insecticidal, acaricidal and molluscicidal agents AMERICAN CYANAMID CO (US) 1999-10-20 CN claimed
EP-0594942-B1 N-aminoalkylcarbonyloxyalkylpyrrole insecticidal acaricidal and molluscicidal agents AMERICAN CYANAMID CO (US) 1996-09-04 EP claimed
JP-58109418-A None JP disclosed
US-20240399776-A1 COLOR DEVELOPER, THERMAL RECORDING MATERIAL, AND THERMAL RECORDING LAYER COATING MATERIAL SANKO CO., LTD. (JP) 2024-12-05 US disclosed
WO-2024034666-A1 RUTHENIUM COMPLEX, METHOD FOR PRODUCING SAME, CATALYST COMPOSITION, OXIDATION METHOD AND METHOD FOR PRODUCING OXYGEN-CONTAINING COMPOUND 国立大学法人九州大学 2024-02-15 WO disclosed
WO-1994023767-A1 ORAL DRUG DELIVERY COMPOSITIONS AND METHODS EMISPHERE TECHNOLOGIES, INC. (US) 1994-10-27 WO disclosed
EP-0553962-A1 Corrosion inhibiting compositions CIBA-GEIGY AG (CH) 1993-08-04 EP disclosed
US-4632931-A ANTICOAGULANTS, BRONCHODILATOR AGENTS E. R. SQUIBB & SONS, INC. (US) 1986-12-30 US disclosed
JP-S58109418-A ALDOSE REDUCTASE INHIBITOR OKUDA JUN 1983-06-29 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215893-A1 Parakeratosis inhibitor, pore-shrinking agent,or rough skin preventing/ameliorating agent, and external composition for skin CUTA, STOM, MTOR MMP1 755/4885GAA 1046/4885MMP12 1873/4885
US-20130165446-A1 BENZO-OR PYRIDO-IMIDAZOLE DERIVATIVE PPARG, PPARA, PPARD MMP1 3426/4885GAA 2338/4885MMP12 2760/4885
US-20040063725-A1 Novel n(phenylsulphonyl)glycine derivatives and their therapeutic use GLS, GLS2, GLRB MMP1 3029/4885GAA 492/4885MMP12 1033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.