Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13256359 | 0.98 | HTR2A (0.42) | HTR2APDK2PDE3BPDE3ANOTUM | |
| SCHEMBL23080562 | 0.92 | POLQ (0.41) | HTR2APDK2PDE3BPDE3ANOTUM | |
| SCHEMBL22561855 | 0.80 | POLQ (0.37) | HTR2APDE3BPDE3ANOTUMPOLQ | |
| SCHEMBL21872092 | 0.79 | APP (0.43) | PDK2ACMSDAPPBACE1EPHX2 | |
| SCHEMBL13256372 | 0.79 | ADCY8 (0.45) | HTR2APDK2POLQARACMSD | |
| SCHEMBL21872202 | 0.79 | APP (0.43) | PDK2ACMSDAPPBACE1EPHX2 | |
| SCHEMBL21241109 | 0.79 | ACMSD (0.38) | PDK2ACMSDAPPBACE1EPHX2 | |
| SCHEMBL21872033 | 0.79 | APP (0.43) | PDK2ACMSDAPPBACE1EPHX2 | |
| SCHEMBL13256360 | 0.79 | ADCY8 (0.45) | HTR2APDK2POLQARACMSD | |
| SCHEMBL21940779 | 0.78 | S1PR1 (0.41) | HTR2APDK2ACMSDAPPBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200115357-A1 | LIVER X RECEPTORS (LXR) MODULATORS | PHENEX-FXR GMBH (DE) | 2020-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200115357-A1 | LIVER X RECEPTORS (LXR) MODULATORS | NR1H2, NR1H3, NR1H4 | HTR2A 1671/4885PDK2 3095/4885PDE3B 4235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.