Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | CES1 | P23141 | 4/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3003271 | 0.86 | CES1 (0.52) | MDM2TDP1L3MBTL1LMNACES1 | |
| SCHEMBL507732 | 0.76 | CES1 (0.50) | TDP1L3MBTL1LMNACES1PGR | |
| SCHEMBL418270 | 0.74 | TDP1 (0.50) | MDM2TDP1L3MBTL1LMNACES1 | |
| SCHEMBL28567881 | 0.73 | CES1 (0.52) | TDP1L3MBTL1LMNACES1CES2 | |
| SCHEMBL27384600 | 0.72 | CES1 (0.50) | TDP1L3MBTL1LMNACES1PGR | |
| SCHEMBL8463346 | 0.72 | CES1 (0.50) | TDP1L3MBTL1LMNACES1PGR | |
| SCHEMBL6699073 | 0.72 | CES1 (0.50) | TDP1L3MBTL1LMNACES1PGR | |
| Methyl Alcohol SCHEMBL27531298 | 0.72 | TDP1 (0.48) | MDM2TDP1L3MBTL1LMNACES1 | |
| SCHEMBL13647200 | 0.71 | CES1 (0.59) | TDP1L3MBTL1LMNACES1PGR | |
| SCHEMBL1645556 | 0.71 | CES1 (0.48) | TDP1L3MBTL1LMNACES1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181001-B1 | SUNSCREEN COMPOSITION CONTAINING SOL-GEL MICROCAPSULES | SOL GEL TECHNOLOGIES LTD (IL) | 2011-07-13 | — | — | EP | claimed |