SCHEMBL3003271

SCHEMBL3003271

CC(C)C(C(=O)c1ccccc1)(C(=O)c1ccccc1)C(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 6/20 0.52
SRC P12931 1/20 0.47
MAPT P10636 2/20 0.45
LMNA P02545 1/20 0.45
XBP1 P17861 1/20 0.45
ATM Q13315 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
TDP1 Q9NUW8 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
MLYCD O95822 1/20 0.45
CES2 O00748 4/20 0.44
TSHR P16473 3/20 0.44
DAO P14920 1/20 0.44
NAPRT Q6XQN6 1/20 0.44
ALDH1A1 P00352 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
PGR P06401 1/20 0.41
ADRA2A P08913 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2187223 0.86 MDM2 (0.47) CES1SRCMAPTLMNAXBP1
SCHEMBL28567881 0.81 CES1 (0.52) CES1SRCMAPTLMNAXBP1
SCHEMBL27384600 0.80 CES1 (0.50) CES1SRCMAPTLMNAXBP1
SCHEMBL6699073 0.80 CES1 (0.50) CES1SRCMAPTLMNAXBP1
SCHEMBL8463346 0.80 CES1 (0.50) CES1SRCMAPTLMNAXBP1
SCHEMBL507732 0.80 CES1 (0.50) CES1SRCMAPTLMNAXBP1
SCHEMBL13647200 0.78 CES1 (0.59) CES1SRCMAPTLMNAXBP1
SCHEMBL10493250 0.77 CYP1A2 (0.48) CES1SRCMAPTLMNAXBP1
SCHEMBL9005042 0.75 CES1 (0.55) CES1SRCMAPTLMNAXBP1
SCHEMBL3349927 0.75 CYP1A2 (0.52) CES1SRCMAPTLMNAXBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114699328-A Photoprotective compositions 欧莱雅 2022-07-05 CN claimed
CN-101316577-B Personal care compositions containing silicone resins with enhanced properties and methods of making and using the same MOMENTIVE PERFORMANCE MAT INC 2015-07-15 CN claimed
CN-101031277-B Use of photostabilized cosmetic or dermatological composition CIBA SPEC CHEM CORP 2012-12-05 CN claimed
CN-101505717-A Photostable cosmetic compositions UNILEVER NV (NL) 2009-08-12 CN claimed
CN-101316577-A Personal care compositions containing silicone resins with enhanced properties and methods of making and using the same MOMENTIVE PERFORMANCE MAT INC (US) 2008-12-03 CN claimed
CN-101219093-A Cosmetic composition containing a dibenzoylmethane derivative and a siloxanic benzoate arylalkyl amide derivative OREAL (FR) 2008-07-16 CN claimed
WO-2008067928-A1 UV ABSORBING COMPOSITIONS CONTAINING A PYRROLYLTRIAZINE ISDIN S.A. (ES) 2008-06-12 WO claimed
CN-101095648-A Dibenzoylmethane sunscreens photostabilized with arylalkyl amide or ester compounds OREAL (FR) 2008-01-02 CN claimed
CN-1798538-A Photostable organic sunscreen composition MERCK PATENT GMBH (DE) 2006-07-05 CN claimed
EP-1635777-A1 PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION MERCK PATENT GmbH (DE) 2006-03-22 EP claimed
CN-1425366-A Anti-sun light cosmetic composition based on sun screening agent synergic mixture and its use OREAL (FR) 2003-06-25 CN claimed
CN-1424018-A San screener containing 1,3,5-triazine derivative, dibenzoylmethane derivative and amino substitued 2-hydroxy-benzene ketone derivative OREAL (FR) 2003-06-18 CN claimed
CN-1092514-C Photostable screening composition comprising dibenzoylmethane derivative and polysaccharide alkyl ether, and uses thereof OREAL (FR) 2002-10-16 CN claimed
CN-1352544-A Material containing organic UV-A sunscreen agent and method for shifting maximum absorption wavelength OREAL (FR) 2002-06-05 CN claimed
CN-1327379-A Method for improving UV radiation stability of photosensitive sunscreen filters OREAL (FR) 2001-12-19 CN claimed
US-20010026789-A1 Photostabilized sunscreen compositions comprising dibenzoylmethane compounds and benzylidenecamphor-substituted silanes/organosiloxanes RICHARD HERVE (FR) 2001-10-04 US claimed
CN-1307468-A Sunscreen composition PROCTER & GAMBLE (US) 2001-08-08 CN claimed
CN-1214239-A Light-screening agents HOFFMANN LA ROCHE (CH) 1999-04-21 CN claimed
CN-1207290-A Cosmetic light-screening composition HOFFMANN LA ROCHE (CH) 1999-02-10 CN claimed
CN-1173324-A Photostable screening composition comprising dibenzoylmethane derivative and polysaccharide alkyl ether, and uses thereof OREAL (FR) 1998-02-18 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010026789-A1 Photostabilized sunscreen compositions comprising dibenzoylmethane compounds and benzylidenecamphor-substituted silanes/organosiloxanes DSG1, DDT, DSC1 CES1 2324/4885SRC 464/4885MAPT 289/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.