SCHEMBL2187255

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6887780	1.00	CHRNA3 (0.69)	CHRNA3HTR3AHTR3EHTR3BCHRNB2
	SCHEMBL6886540	0.83	CHRNA3 (0.71)	CHRNA3HTR3AHTR3EHTR3BCHRNB2
	SCHEMBL6892215	0.83	CHRNA3 (0.71)	CHRNA3HTR3AHTR3EHTR3BCHRNB2
	SCHEMBL6891582	0.82	HTR3A (0.69)	CHRNA3HTR3AHTR3EHTR3BCHRNB2
	SCHEMBL2188457	0.82	CHRNA3 (1.00)	CHRNA3HTR3AHTR3EHTR3BCHRNB2
	SCHEMBL2190762	0.82	CHRNA7 (0.69)	CHRNA3HTR3AHTR3EHTR3BCHRNB2
	SCHEMBL6887110	0.82	HTR3A (0.69)	CHRNA3HTR3AHTR3EHTR3BCHRNB2
	SCHEMBL6886384	0.82	CHRNA3 (1.00)	CHRNA3HTR3AHTR3EHTR3BCHRNB2
	SCHEMBL6887440	0.82	CHRNA7 (0.69)	CHRNA3HTR3AHTR3EHTR3BCHRNB2
	SCHEMBL6887585	0.82	HTR3A (0.69)	CHRNA3HTR3AHTR3EHTR3BCHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.