SCHEMBL21873552

SCHEMBL21873552

Cc1cccc(C)c1P(c1c(C)cccc1C)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.40
P2RX7 Q99572 3/20 0.40
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39
GRIN3A Q8TCU5 1/20 0.39
CNR2 P34972 3/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
MAPT P10636 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
HSD11B1 P28845 1/20 0.34
POLB P06746 1/20 0.33
TSHR P16473 1/20 0.33
ACHE P22303 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21873550 0.85 SIGMAR1 (0.36) SIGMAR1P2RX7GRIN2DGRIN3BGRIN1
SCHEMBL15656865 0.81 SIGMAR1 (0.40) SIGMAR1P2RX7GRIN2DGRIN3BGRIN1
SCHEMBL15657435 0.80 MEN1 (0.39) SIGMAR1P2RX7GRIN2DGRIN3BGRIN1
SCHEMBL30402889 0.76 SIGMAR1 (0.39) SIGMAR1P2RX7GRIN2DGRIN3BGRIN1
SCHEMBL15275551 0.76 SIGMAR1 (0.39) SIGMAR1P2RX7GRIN2DGRIN3BGRIN1
SCHEMBL15658232 0.73 MEN1 (0.39) SIGMAR1P2RX7GRIN2DGRIN3BGRIN1
SCHEMBL15660455 0.71 FAAH (0.39) P2RX7GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL15656866 0.71 LMNA (0.37) P2RX7GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL15656876 0.70 MEN1 (0.34) SIGMAR1P2RX7GRIN2DGRIN3BGRIN1
Amantadine SCHEMBL27831277 0.69 GRIN2D (0.56) SIGMAR1P2RX7GRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3892611-B1 METHOD FOR PRODUCING FLUOROVINYL AMIDE COMPOUND DAIKIN IND LTD (JP) 2026-01-28 EP disclosed
US-20250214936-A1 METHOD FOR PRODUCING FLUOROVINYL AMIDE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2025-07-03 US disclosed
US-12281075-B2 Method for producing fluorovinyl amide compound DAIKIN INDUSTRIES, LTD. (JP) 2025-04-22 US disclosed
US-11932596-B2 Fluorovinyl ether compound DAIKIN INDUSTRIES, LTD. (JP) 2024-03-19 US disclosed
EP-3643694-B1 METHOD FOR PRODUCING BUTADIENE COMPOUND DAIKIN IND LTD (JP) 2023-11-15 EP disclosed
US-20230144907-A1 METHOD FOR PRODUCING FLUOROVINYL ETHER COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2023-05-11 US disclosed
US-11560347-B2 Method for producing fluorovinyl ether compound DAIKIN INDUSTRIES, LTD. (JP) 2023-01-24 US disclosed
US-20220055990-A1 METHOD FOR PRODUCING FLUOROVINYL AMIDE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2022-02-24 US disclosed
EP-3892611-A1 METHOD FOR PRODUCING FLUOROVINYL AMIDE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2021-10-13 EP disclosed
US-20210284593-A1 METHOD FOR PRODUCING FLUOROVINYL ETHER COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2021-09-16 US disclosed
EP-3816146-A1 METHOD FOR PRODUCING FLUOROVINYL ETHER COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2021-05-05 EP disclosed
WO-2020116589-A1 METHOD FOR PRODUCING FLUOROVINYL AMIDE COMPOUND ダイキン工業株式会社 2020-06-11 WO disclosed
EP-3643694-A1 METHOD FOR PRODUCING BUTADIENE COMPOUND Daikin Industries, Ltd. (JP) 2020-04-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230144907-A1 METHOD FOR PRODUCING FLUOROVINYL ETHER COMPOUND RB1, AFF1, AFF2 SIGMAR1 4450/4885P2RX7 4146/4885GRIN2D 3377/4885
US-11932596-B2 Fluorovinyl ether compound RB1, AFF1, AFF2 SIGMAR1 4288/4885P2RX7 3698/4885GRIN2D 3569/4885
US-12281075-B2 Method for producing fluorovinyl amide compound RB1, KRAS, NRAS SIGMAR1 4094/4885P2RX7 4597/4885GRIN2D 2392/4885
US-20250214936-A1 METHOD FOR PRODUCING FLUOROVINYL AMIDE COMPOUND RB1, KRAS, NRAS SIGMAR1 4094/4885P2RX7 4597/4885GRIN2D 2392/4885
US-20220055990-A1 METHOD FOR PRODUCING FLUOROVINYL AMIDE COMPOUND RB1, KRAS, NRAS SIGMAR1 4094/4885P2RX7 4597/4885GRIN2D 2392/4885
US-20210284593-A1 METHOD FOR PRODUCING FLUOROVINYL ETHER COMPOUND RB1, AFF1, AFF2 SIGMAR1 4450/4885P2RX7 4146/4885GRIN2D 3377/4885
US-11560347-B2 Method for producing fluorovinyl ether compound ETV6, CYP2F1, CYP4F2 SIGMAR1 4138/4885P2RX7 4349/4885GRIN2D 2966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.