SCHEMBL2187422

SCHEMBL2187422

C=CCOCC(C)OC(=O)C(=C)C

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 1/20 0.33
THRB P10828 1/20 0.33
CA4 P22748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2148367 0.95 TSHR (0.40) TSHRCA1CA2CA7CA9
SCHEMBL17109947 0.92 TSHR (0.40) TSHRCA1CA2CA7TDP1
SCHEMBL28437216 0.87 TSHR (0.39) TSHRCA1CA2CA7CA9
SCHEMBL2219398 0.85 TSHR (0.52) TSHRTDP1ALDH1A1THRB
SCHEMBL28429808 0.85 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL5598469 0.85 TSHR (0.40) TSHRTDP1THRB
SCHEMBL3952800 0.84 TSHR (0.40) TSHRCA1CA2CA7CA9
SCHEMBL243615 0.84 TSHR (0.42) TSHRCA1CA2CA7CA9
SCHEMBL17109944 0.83 THRB (0.46) TSHRCA1CA2CA7CA9
SCHEMBL28429807 0.82 TSHR (0.40) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107771199-B Process for making crosslinked cable insulation using high melt strength ethylene-based polymers made in a tubular reactor and optionally modified with a branching agent 陶氏环球技术有限责任公司 2021-05-25 CN claimed
EP-1272334-B1 COMPOSITIONS AND METHOD FOR THREE-DIMENSIONAL PRINTING OF SOLID OBJECTS 3D SYSTEMS INC (US) 2012-11-14 EP claimed
EP-2342588-B9 IONIC SILICONE HYDROGELS HAVING IMPROVED HYDROLYTIC STABILITY JOHNSON & JOHNSON VISION CARE (US) 2024-10-02 EP disclosed
EP-2342588-B1 IONIC SILICONE HYDROGELS HAVING IMPROVED HYDROLYTIC STABILITY JOHNSON & JOHNSON VISION CARE (US) 2024-07-03 EP disclosed
CN-114622406-B Piezoresistive yarn preparation method and piezoresistive yarn prepared by same 水木山海科技(佛山)有限责任公司 2023-10-13 CN disclosed
US-20230287157-A1 Ethylene-Based Polymer Composition with Multifunctional Branching Agent and Process for Producing Same DOW GLOBAL TECHNOLOGIES LLC 2023-09-14 US disclosed
US-20230287157-A1 Ethylene-Based Polymer Composition with Multifunctional Branching Agent and Process for Producing Same DOW GLOBAL TECHNOLOGIES LLC 2023-09-14 US disclosed
CN-114622406-A Piezoresistive yarn preparation method and piezoresistive yarn prepared by piezoresistive yarn preparation method 佛山(华南)新材料研究院 2022-06-14 CN disclosed
CN-111542554-B Polymer, curable resin composition, and use thereof 株式会社日本触媒 2022-03-18 CN disclosed
CN-107771199-B Process for making crosslinked cable insulation using high melt strength ethylene-based polymers made in a tubular reactor and optionally modified with a branching agent 陶氏环球技术有限责任公司 2021-05-25 CN disclosed
CN-107750259-B Vinyl polymers having low hexane extractables and low density 陶氏环球技术有限责任公司 2021-04-09 CN disclosed
EP-2038683-A2 PROCESS FOR MAKING OPHTHALMIC LENSES Johnson and Johnson Vision Care, Inc. (US) 2009-03-25 EP disclosed
WO-2008091114-A1 PHOTO-CURABLE COMPOSITION HAVING INHERENTLY EXCELLENT RELEASING PROPERTY AND PATTERN TRANSFER PROPERTY, METHOD FOR TRANSFERRING PATTERN USING THE COMPOSITION AND LIGHT RECORDING MEDIUM HAVING POLYMER PATTERN LAYER PRODUCED USING THE COMPOSITION SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-07-31 WO disclosed
WO-2008054651-A2 PROCESS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES JOHNSON & JOHNSON VISION CARE, INC. (US) 2008-05-08 WO disclosed
WO-2008054667-A1 PROCESS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES JOHNSON & JOHNSON VISION CARE, INC. (US) 2008-05-08 WO disclosed
US-20080103231-A1 PROCESS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES JOHNSON & JOHNSON VISION CARE, INC. 2008-05-01 US disclosed
US-20080061457-A1 Manufacturing Method of Acrylic Optical Fiber with Improved Environmental Stability NANOPTICS, INCORPORATED (US) 2008-03-13 US disclosed
WO-2008005229-A2 PROCESS FOR MAKING OPHTHALMIC LENSES JOHNSON & JOHNSON VISION CARE, INC. (US) 2008-01-10 WO disclosed
US-20070222095-A1 PROCESS FOR MAKING OPHTHALMIC LENSES JOHNSON & JOHNSON VISION CARE, INC. 2007-09-27 US disclosed
US-20070138692-A1 PROCESS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES JOHNSON & JOHNSON VISION CARE, INC. 2007-06-21 US disclosed