Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.40 |
| ▸ | P2RX2 | Q9UBL9 | 5/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21875085 | 0.88 | WDR5 (0.45) | WDR5KLKB1P2RX3P2RX2NAMPT | |
| SCHEMBL21875180 | 0.87 | KLKB1 (0.50) | ALDH1A1KLKB1P2RX3P2RX2NAMPT | |
| SCHEMBL21875100 | 0.86 | WDR5 (0.46) | WDR5P2RX3P2RX2 | |
| SCHEMBL21875093 | 0.86 | NAMPT (0.46) | WDR5ALDH1A1GRM4KLKB1NAMPT | |
| SCHEMBL21875087 | 0.86 | P2RX3 (0.44) | WDR5KLKB1P2RX3P2RX2NAMPT | |
| SCHEMBL21875086 | 0.85 | KLKB1 (0.49) | WDR5ALDH1A1KLKB1P2RX3P2RX2 | |
| SCHEMBL21875065 | 0.84 | WDR5 (0.47) | WDR5GRM4KLKB1P2RX3P2RX2 | |
| SCHEMBL21875162 | 0.84 | WDR5 (0.45) | WDR5ALDH1A1KLKB1P2RX3P2RX2 | |
| SCHEMBL21875168 | 0.83 | KLKB1 (0.47) | WDR5ALDH1A1KLKB1P2RX3P2RX2 | |
| SCHEMBL21875129 | 0.82 | P2RX3 (0.44) | WDR5KLKB1P2RX3P2RX2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113056461-A | Arylsulfonyl pyrrole carboxamide derivatives as Kv3 potassium channel activators | H.隆德贝克有限公司 | 2021-06-29 | — | — | CN | claimed |
| US-20200131156-A1 | ARYLSULFONYLPYROLECARBOXAMIDE DERIVATIVES AS Kv3 POTASSIUM CHANNEL ACTIVATORS | H. LUNDBECK A/S (DK) | 2020-04-30 | — | — | US | claimed |
| CN-113056461-A | Arylsulfonyl pyrrole carboxamide derivatives as Kv3 potassium channel activators | H.隆德贝克有限公司 | 2021-06-29 | — | — | CN | disclosed |
| US-20200131156-A1 | ARYLSULFONYLPYROLECARBOXAMIDE DERIVATIVES AS Kv3 POTASSIUM CHANNEL ACTIVATORS | H. LUNDBECK A/S (DK) | 2020-04-30 | — | — | US | disclosed |
| US-20200131156-A1 | ARYLSULFONYLPYROLECARBOXAMIDE DERIVATIVES AS Kv3 POTASSIUM CHANNEL ACTIVATORS | H. LUNDBECK A/S (DK) | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131156-A1 | ARYLSULFONYLPYROLECARBOXAMIDE DERIVATIVES AS Kv3 POTASSIUM CHANNEL ACTIVATORS | KCNA3, KCNN3, KCNK3 | WDR5 2656/4885KDM4E 247/4885ALDH1A1 4451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.