Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | TTPA | P49638 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 4/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | PHLPP1 | O60346 | 1/20 | 0.36 |
| ▸ | ILK | Q13418 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21875426 | 1.00 | LMNA (0.43) | LMNAMAPTMEN1GSTP1TTPA | |
| SCHEMBL21875425 | 1.00 | LMNA (0.43) | LMNAMAPTMEN1GSTP1TTPA | |
| SCHEMBL21929589 | 0.82 | LMNA (0.55) | LMNAMAPTMEN1GSTP1TTPA | |
| SCHEMBL21929591 | 0.82 | LMNA (0.55) | LMNAMAPTMEN1GSTP1TTPA | |
| SCHEMBL9285268 | 0.82 | LMNA (0.55) | LMNAMAPTMEN1GSTP1TTPA | |
| SCHEMBL21931411 | 0.82 | LMNA (0.55) | LMNAMAPTMEN1GSTP1TTPA | |
| SCHEMBL21131789 | 0.82 | LMNA (0.55) | LMNAMAPTMEN1GSTP1TTPA | |
| SCHEMBL21931412 | 0.82 | LMNA (0.55) | LMNAMAPTMEN1GSTP1TTPA | |
| SCHEMBL2635649 | 0.77 | LMNA (0.43) | LMNAMAPTMEN1GSTP1TTPA | |
| SCHEMBL9356911 | 0.76 | AKT1 (0.48) | LMNAMAPTMEN1GSTP1TTPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11724996-B2 | Synthesis of intermediates for the preparation of alpha-tocopherol | DSM IP ASSETS B.V. (NL) | 2023-08-15 | — | — | US | disclosed |
| EP-3652162-B1 | NOVEL SYNTHESIS OF INTERMEDIATES FOR THE PREPARATION OF ALPHA-TOCOPHEROL | DSM IP ASSETS BV (NL) | 2023-02-22 | — | — | EP | disclosed |
| US-20210300886-A1 | SYNTHESIS OF INTERMEDIATES FOR THE PREPARATION OF ALPHA-TOCOPHEROL | DSM IP ASSETS BV (NL) | 2021-09-30 | — | — | US | disclosed |
| US-20200131145-A1 | NOVEL SYNTHESIS OF INTERMEDIATES FOR THE PREPARATION OF ALPHA-TOCOPHEROL | DSM IP ASSETS B.V. (NL) | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300886-A1 | SYNTHESIS OF INTERMEDIATES FOR THE PREPARATION OF ALPHA-TOCOPHEROL | TTPA, DHPS, SQLE | LMNA 1425/4885MAPT 4091/4885MEN1 3040/4885 |
| US-20200131145-A1 | NOVEL SYNTHESIS OF INTERMEDIATES FOR THE PREPARATION OF ALPHA-TOCOPHEROL | TTPA, VKORC1, SQLE | LMNA 1413/4885MAPT 3971/4885MEN1 2894/4885 |
| US-11724996-B2 | Synthesis of intermediates for the preparation of alpha-tocopherol | TTPA, DHPS, SQLE | LMNA 1425/4885MAPT 4091/4885MEN1 3040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.