SCHEMBL2187676

SCHEMBL2187676

CC(Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)P(=O)(O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 3/20 0.60
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
GAA P10253 3/20 0.48
ALDH1A1 P00352 7/20 0.46
TSHR P16473 3/20 0.46
MAPK1 P28482 3/20 0.46
MAPT P10636 3/20 0.46
CYP1A2 P05177 2/20 0.46
CYP3A4 P08684 2/20 0.46
BLM P54132 2/20 0.46
ATM Q13315 2/20 0.46
HIF1A Q16665 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
USP2 O75604 1/20 0.46
CYP2D6 P10635 1/20 0.46
LMNA P02545 3/20 0.46
GMNN O75496 1/20 0.45
GABBR2 O75899 1/20 0.45
TP53 P04637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Calcium SCHEMBL2278710 0.98 HMGCR (0.58) HMGCRMEN1KMT2AGAAALDH1A1
SCHEMBL6370947 0.85 HMGCR (0.66) HMGCRMEN1KMT2AGAAALDH1A1
SCHEMBL1887921 0.84 HMGCR (0.57) HMGCRMEN1KMT2AGAAALDH1A1
SCHEMBL5523318 0.84 HMGCR (0.57) HMGCRMEN1KMT2AGAAALDH1A1
SCHEMBL2280824 0.84 HMGCR (0.57) HMGCRMEN1KMT2AGAAALDH1A1
SCHEMBL8154654 0.80 HMGCR (0.59) HMGCRMEN1KMT2AGAAALDH1A1
SCHEMBL10426640 0.80 HMGCR (0.63) HMGCRMEN1KMT2AGAAALDH1A1
SCHEMBL9373479 0.80 HMGCR (0.52) HMGCRMEN1KMT2AGAAALDH1A1
SCHEMBL78134 0.79 MEN1 (0.61) HMGCRMEN1KMT2AGAAALDH1A1
SCHEMBL11647680 0.78 HMGCR (0.42) HMGCRMEN1KMT2AGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2840112-B1 Stabilized polymer compositions and methods of making same BAERLOCHER GMBH (DE) 2019-04-10 EP claimed
EP-1925628-A1 Process for polyolefin silane crosslinking Ciba Holding Inc. (CH) 2008-05-28 EP claimed
US-12577415-B2 Associative rheology modifier composition and methods for making thereof Kraton Corporation (US) 2026-03-17 US disclosed
EP-4092085-B1 ASSOCIATIVE RHEOLOGY MODIFIER COMPOSITION AND METHODS FOR MAKING THEREOF KRATON POLYMERS RES BV (NL) 2025-01-01 EP disclosed
US-20240218131-A1 A MASTERBATCH FOR UPGRADING POLYESTERS NEXAM CHEMICAL AB (SE) 2024-07-04 US disclosed
EP-4363220-A1 PROPYLENE TERPOLYMER AND HEAT SEAL FILMS MADE THEREFROM W. R. Grace & Co.-Conn (US) 2024-05-08 EP disclosed
EP-4351866-A1 POLYPROPYLENE RANDOM COPOLYMER FOR THREE-DIMENSIONAL PRINTING AND FILAMENT MADE THEREFROM W. R. Grace & Co.-Conn (US) 2024-04-17 EP disclosed
US-20240018346-A1 HIGH CRYSTALLINE OLEFIN POLYMER FOR HIGH SPEED SPINNING W.R. GRACE & CO.-CONN. (US) 2024-01-18 US disclosed
EP-4259699-A1 HIGH CRYSTALLINE OLEFIN POLYMER FOR HIGH SPEED SPINNING W. R. Grace & Co.-Conn (US) 2023-10-18 EP disclosed
EP-3397709-B1 OLIGOESTERS AND COMPOSITIONS THEREOF KRATON CHEMICAL LLC (US) 2023-10-11 EP disclosed
EP-4083114-B1 A MASTERBATCH FOR UPGRADING POLYESTERS NEXAM CHEMICAL AB (SE) 2023-08-02 EP disclosed
EP-0334051-B1 Electron beam-curable composition for release material and process for preparation of release material SHOWA DENKO KK (JP) 1996-05-01 EP disclosed
EP-0375781-B1 ELECTRET MATERIAL AND PROCESS FOR PREPARING ELECTRET MATERIAL TORAY INDUSTRIES (JP) 1994-01-19 EP disclosed
EP-0565868-A2 Polyethylene insulation composition QUANTUM CHEMICAL CORPORATION (US) 1993-10-20 EP disclosed
US-5206092-A Irradiating a composition of polyolefin resin, dimethylsiloxane and a polyfunctional compound having unsaturation or thiol groups SHOWA DENKO K.K. (JP) 1993-04-27 US disclosed
US-5057710-A ELECTRET MATERIALS AND THE METHOD FOR PREPARING THE ELECTRET MATERIALS TORAY INDUSTRIES, INC. (JP) 1991-10-15 US disclosed
EP-0375781-A1 ELECTRET MATERIAL AND PROCESS FOR PREPARING ELECTRET MATERIAL TORAY INDUSTRIES, INC. (JP) 1990-07-04 EP disclosed
US-4401804-A Deactivation of polyester catalyst residues EASTMAN KODAK COMPANY (US) 1983-08-30 US disclosed
US-4352861-A MULTILAYER, POLYOLEFIN, STABILIZERS FELIX SCHOELLER, JR. GMBH & CO. KG (DE) 1982-10-05 US disclosed
EP-0013665-A1 Polymeric polyamino 1,3,5-triazines containing at least one polyalkylpiperidine group, their preparation, their use in stabilizing an organic material and the material stabilized therewith CIBA-GEIGY AG (CH) 1980-07-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577415-B2 Associative rheology modifier composition and methods for making thereof GPX4, RO60, SCLY HMGCR 2924/4885MEN1 1245/4885KMT2A 3043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.