SCHEMBL21881

SCHEMBL21881

C=Cc1cccc(C=C)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.67
TP53 P04637 1/20 0.67
ALDH1A1 P00352 3/20 0.61
TSHR P16473 1/20 0.61
PTGS2 P35354 1/20 0.44
HDAC8 Q9BY41 2/20 0.42
TRPA1 O75762 1/20 0.38
NFE2L2 Q16236 2/20 0.38
FBP1 P09467 1/20 0.37
FURIN P09958 1/20 0.36
NPC1 O15118 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
PKM P14618 1/20 0.33
MAPK1 P28482 1/20 0.33
THPO P40225 1/20 0.33
CHRM5 P08912 1/20 0.33
GRM5 P41594 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30381592 0.97 TDP1 (0.64) TDP1TP53ALDH1A1TSHRPTGS2
Water SCHEMBL20239051 0.97 TDP1 (0.64) TDP1TP53ALDH1A1TSHRPTGS2
Ammonia Solution, Strong SCHEMBL31335086 0.97 TDP1 (0.64) TDP1TP53ALDH1A1TSHRPTGS2
Hydrochloric Acid SCHEMBL29128956 0.94 TDP1 (0.61) TDP1TP53ALDH1A1TSHRPTGS2
Styrene SCHEMBL9639895 0.91 ALDH1A1 (0.78) TDP1TP53ALDH1A1TSHRPTGS2
SCHEMBL29128955 0.89 TP53 (0.56) TDP1TP53ALDH1A1TSHRPTGS2
SCHEMBL614580 0.87 TP53 (0.60) TDP1TP53ALDH1A1TSHRPTGS2
SCHEMBL16959211 0.87 TDP1 (0.54) TDP1TP53ALDH1A1TSHRPTGS2
SCHEMBL149900 0.87 ALDH1A1 (0.54) TDP1TP53ALDH1A1TSHRPTGS2
SCHEMBL7561071 0.87 TP53 (0.54) TDP1TP53ALDH1A1TSHRPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4931 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121717957-B Modified polyethylene and preparation method and application thereof 北京怀柔实验室 2026-05-12 CN claimed
US-20260055260-A1 STABILIZER FOR SUPPRESSING GENERATION OF SILANE FROM A POLYSILANE COMPOSITION AND METHOD FOR SUPPRESSING GENERATION OF SILANE MERCK PATENT GMBH (DE) 2026-02-26 US claimed
US-12545780-B2 Flexible metal clad laminates and methods of preparation thereof NOTARK CORPORATION (US) 2026-02-10 US claimed
US-20260008743-A1 PROCESS FOR PRODUCING POLYUNSATURATED FATTY ACIDS IN THE FORM OF ESTERS ENI S.P.A. (IT) 2026-01-08 US claimed
EP-4045585-B1 POLYBUTYLENE TEREPHTHALATE COMPOSITION AND ARTICLE THEREOF BASF SE (DE) 2025-12-10 EP claimed
CN-120118238-A Narrow-band luminous microsphere and preparation method thereof 海南大学 2025-06-10 CN claimed
CN-120081762-A Tetramethyl room xylylene group method for synthesizing dicarbamate 湖南方锐达科技有限公司 2025-06-03 CN claimed
CN-120025482-A Polymer microsphere and ammonia nitrogen remover as well as preparation method and application thereof 上海丁香环境科技有限公司 2025-05-23 CN claimed
US-20250154352-A1 POLYBUTYLENE TEREPHTHALATE COMPOSITION BASF SE (DE) 2025-05-15 US claimed
CN-119955037-A Double-ended siloxane-based styrene-butadiene polymer, preparation method thereof, rubber composition and vulcanized rubber 中国石油天然气股份有限公司 2025-05-09 CN claimed
US-4248980-A FROM A MONOVINYL AROMATIC COMPOUND AND A CONJUGATED DIENE ARCO POLYMERS, INC. (US) 1981-02-03 US claimed
US-4248981-A FROM A MONOVINYL AROMATIC COMPOUND AND A CONJUGATED DIENE ARCO POLYMERS, INC. (US) 1981-02-03 US claimed
US-4248982-A FROM A MONOVINYL AROMATIC COMPOUND AND A CONJUGATED DIENE ARCO POLYMERS, INC. (US) 1981-02-03 US claimed
US-4247474-A POLYFUNCTIONAL ALKYLENE, CYCLOALKYLENE, OR ARYLENE DERIVATIVES; HYDROGEN CHLORIDE SALTS USED AS CURING AGENTS HERCULES INCORPORATED (US) 1981-01-27 US claimed
US-4221884-A MONOVINYLAROMATIC-CONJUGATED DIENE INTERPOLYMER ARCO POLYMERS, INC. (US) 1980-09-09 US claimed
US-4180530-A OLEFIN AROMATIC-POLYENES CONJUGATED COPOLYMER ARCO POLYMERS, INC. (US) 1979-12-25 US claimed
US-4012317-A Process for extracting urea from a solution with alkenylaromatic polymers with α-ketoalhydic groups RHONE-POULENC S.A. (FR) 1977-03-15 US claimed
US-4007138-A Manufacture of ion-exchanging shaped articles BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1977-02-08 US claimed
US-3985830-A NUCLEUS OF POLY-M-DIVINYLBENZENE HAVING ARMS OF POLYMERS OF CONJUGATED DIENES ANDOR AROMATIC VINYLS THE UNIVERSITY OF AKRON (US) 1976-10-12 US claimed
US-3933753-A Alkenylaromatic polymers with α-ketoalhydic groups RHONE-POULENC S.A. (FR) 1976-01-20 US claimed