SCHEMBL614580

SCHEMBL614580

C=Cc1cccc([CH]C)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
ALDH1A1 P00352 3/20 0.48
TSHR P16473 1/20 0.48
PTGS2 P35354 1/20 0.42
HDAC8 Q9BY41 2/20 0.40
TRPA1 O75762 1/20 0.36
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
NPC1 O15118 1/20 0.32
CASP3 P42574 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
FBP1 P09467 1/20 0.31
NFE2L2 Q16236 1/20 0.31
APP P05067 4/20 0.31
TGFBR1 P36897 1/20 0.31
FURIN P09958 1/20 0.30
BRD2 P25440 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21881 0.87 TDP1 (0.67) TP53TDP1ALDH1A1TSHRPTGS2
SCHEMBL2186055 0.87 TP53 (0.40) TP53TDP1ALDH1A1PKMNPC1
Water SCHEMBL20239051 0.84 TDP1 (0.64) TP53TDP1ALDH1A1TSHRPTGS2
Ammonia Solution, Strong SCHEMBL31335086 0.84 TDP1 (0.64) TP53TDP1ALDH1A1TSHRPTGS2
SCHEMBL30381592 0.84 TDP1 (0.64) TP53TDP1ALDH1A1TSHRPTGS2
Hydrochloric Acid SCHEMBL29128956 0.81 TDP1 (0.61) TP53TDP1ALDH1A1TSHRPTGS2
SCHEMBL4959089 0.81 TP53 (0.56) TP53TDP1ALDH1A1TSHRPTGS2
Styrene SCHEMBL9639895 0.79 ALDH1A1 (0.78) TP53TDP1ALDH1A1TSHRPTGS2
SCHEMBL29128955 0.77 TP53 (0.56) TP53TDP1ALDH1A1TSHRPTGS2
Toluene SCHEMBL11253136 0.76 TP53 (0.75) TP53TDP1ALDH1A1TSHRPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108845481-A Photosensitive composition 住友化学株式会社 2018-11-20 CN disclosed
CN-108073038-A Colored curable resin composition, the colour filter formed by colored curable resin composition and the display device comprising colour filter 东友精细化工有限公司 2018-05-25 CN disclosed
CN-108073041-A Coloured composition, colored curable resin composition, colour filter and display device 东友精细化工有限公司 2018-05-25 CN disclosed
CN-107783373-A Colored curable resin composition, colour filter and display device 东友精细化工有限公司 2018-03-09 CN disclosed
EP-2857446-B1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2018-03-07 EP disclosed
CN-107698536-A Compound, coloured composition, fibrous material, colour filter and display device 东友精细化工有限公司 2018-02-16 CN disclosed
CN-107522685-A Compound, colored curable resin composition, colour filter and display device 东友精细化工有限公司 2017-12-29 CN disclosed
US-9790359-B2 Tread rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2017-10-17 US disclosed
CN-107111230-A Colored curable resin composition 东友精细化工有限公司 2017-08-29 CN disclosed
CN-107109074-A Compound 东友精细化工有限公司 2017-08-29 CN disclosed
CN-102372825-B Curable resin composition SUMITOMO CHEMICAL CO., LTD. (JP) 2015-11-04 CN disclosed
CN-102207680-B Photosensitive polymer combination SUMITOMO CHEMICAL CO., LTD. (JP) 2015-09-02 CN disclosed
CN-102803274-B Silane coupling agent, negative light-sensitive resin combination, cured film and touch panel component TORAY INDUSTRIES, INC. (JP) 2015-07-29 CN disclosed
US-20150099823-A1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2015-04-09 US disclosed
EP-2857446-A1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2015-04-08 EP disclosed
US-8299179-B2 Conjugated diene-based polymer, conjugated diene-based polymer composition, and process for producing conjugated diene-based polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-30 US disclosed
US-20120041136-A1 CONJUGATED DIENE-BASED POLYMER, CONJUGATED DIENE-BASED POLYMER COMPOSITION, AND PROCESS FOR PRODUCING CONJUGATED DIENE-BASED POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-16 US disclosed
EP-0881250-B1 Process for preparing organosilicon compounds having hydrogen bound to silicon WACKER CHEMIE GMBH (DE) 1999-11-24 EP disclosed
US-5866707-A Process for preparing organosilicon compounds having Si-bonded hydrogen atoms WACKER-CHEMIE GMBH (DE) 1999-02-02 US disclosed
EP-0881250-A1 Process for preparing organosilicon compounds having hydrogen bound to silicon Wacker-Chemie GmbH (DE) 1998-12-02 EP disclosed