SCHEMBL2188141

SCHEMBL2188141

CCCCCC(F)(F)C(F)(OC(F)(C(F)(F)F)C(F)(F)CCCCC)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.36
LPAR1 Q92633 1/20 0.36
LPAR3 Q9UBY5 1/20 0.36
CES1 P23141 6/20 0.34
EPHX1 P07099 1/20 0.31
FAAH O00519 8/20 0.31
SMPD1 P17405 1/20 0.31
TSHR P16473 1/20 0.30
THRB P10828 1/20 0.30
GGPS1 O95749 2/20 0.30
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
KMT2A Q03164 1/20 0.30
HSD17B10 Q99714 1/20 0.30
FDPS P14324 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7633115 0.83
SCHEMBL9974576 0.78 CES2 (0.43) CES2LPAR1LPAR3CES1FAAH
SCHEMBL17510336 0.78 CES2 (0.43) CES2LPAR1LPAR3CES1FAAH
SCHEMBL503761 0.76 CES2 (0.39) CES2LPAR1LPAR3CES1FAAH
SCHEMBL23642215 0.76 CES2 (0.44) CES2LPAR1LPAR3CES1EPHX1
SCHEMBL6037238 0.75 CES2 (0.46) CES2LPAR1LPAR3CES1FAAH
SCHEMBL22268683 0.75 CES2 (0.46) CES2LPAR1LPAR3CES1FAAH
SCHEMBL30892683 0.75 CES2 (0.46) CES2LPAR1LPAR3CES1FAAH
SCHEMBL17510328 0.75 CES2 (0.46) CES2LPAR1LPAR3CES1FAAH
SCHEMBL45268 0.75 CES2 (0.46) CES2LPAR1LPAR3CES1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8465850-B2 Method for the application of active materials onto a surface and devices made with such methods E I DU PONT DE NEMOURS AND COMPANY (US) 2013-06-18 US disclosed
US-8287766-B2 depositing fluorinated aryl ethers and polyanilines or polythiophenes combined with fluorinated polysulfonic acids and/or mixtures, onto glass substrates, useful in organic electronic devices; organic light emitting diodes E I DU PONT DE NEMOURS AND COMPANY (US) 2012-10-16 US disclosed
US-20110180761-A1 METHOD FOR THE APPLICATION OF ACTIVE MATERIALS ONTO A SURFACES AND DEVICES MADE WITH SUCH METHODS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-28 US disclosed
US-7686978-B2 Method for the application of active materials onto active surfaces and devices made with such methods E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-03-30 US disclosed
US-7531700-B2 Fluorinated arylethers and methods for use thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-05-12 US disclosed
US-20050269550-A1 Method for the application of active materials onto active surfaces and devices made with such methods PETROV VIACHESLAV A 2005-12-08 US disclosed
WO-2005030688-A2 FLUORINATED ARYLETHERS AND METHODS FOR USE THEREOF E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-04-07 WO disclosed
WO-2005031889-A2 METHOD FOR THE APPLICATION OF ACTIVE MATERIALS ONTO ACTIVE SURFACES AND DEVICES MADE WITH SUCH METHODS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-04-07 WO disclosed
US-20050062021-A1 Method for the application of active materials onto active surfaces and devices made with such methods LG CHEM, LTD. (KR) 2005-03-24 US disclosed
US-20050065382-A1 Fluorinated arylethers and methods for use thereof E.I. DU PONT DE NEMOURS AND COMPANY 2005-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050065382-A1 Fluorinated arylethers and methods for use thereof CYP2F1, FLI1, AOX1 CES2 84/4885LPAR1 2042/4885LPAR3 1611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.